导师简介-李真宝

发布者:刘芳 发布时间:2018-12-10 浏览次数:

李真宝,男,中共党员,博士,硕士生导师,安徽中医药大学药学院药物制剂研究所研究员,研究方向:智能响应性纳米递送系统。博士期间以第一作者发表SCI论文7篇,其中IF>4.55篇。E-mailsysoloman@163.com; Tel: 0551-68129142.

3年代表性研究论文

  1. Zhenbao Li, Dan Li, Qingsong Li et al. In situ low-immunogenic albumin-conjugating- corona guiding nanoparticles for tumor-targeting chemotherapy. Biomaterials Science, 2018, doi: 10.1039/c8bm00692j.

  2. Zhenbao Li, Dan Li, Wenjuan Zhang et al. Insight into the preformed albumin corona on in vitro and in vivo performances of albumin-selective nanoparticles. Asian Journal of Pharmaceutical Sciences, 2018, doi.org/10.1016/j.ajps.2018.07.002.

  3. Zhenbao Li, Xiaopeng Han, Yinglei Zhai et al. Critical determinant of intestinal permeability and oral bioavailability of pegylated all trans-retinoic acid prodrug-based nanomicelles: Chain length of poly (ethylene glycol) corona. Colloids and Surfaces B: Biointerfaces, 2015, 130: 133–140.

  4. Zhenbao Li, Wenjuan Zhang, Yan Gao et al. Development of self-nanoemulsifying drug delivery system for oral bioavailability enhancement of valsartan in beagle dogs. Drug Delivery. and Translation. Research, 2017, 7:100–110.

  5. Zhenbao Li, Meiyu Zhang, Chang Liu et al. Development of Liposome containing sodium Deoxycholate to enhance oral bioavailability of itraconazole. Asian Journal of Pharmaceutical Sciences, 2017, 157-164

  6. Zhenbao Li, Lei Shang, Chang Liu et al. Evaluation of pharmacokinetics underlies the collaborated usage of lamivudine and oxymatr ine in beagle dogs. Asian Journal of Pharmaceutical Sciences, 2016, 641-647.

  7. Zhenbao Li, Wenhui Tao, Dong Zhang et al. The studies of PLGA nanoparticles loading Atorvastatin calcium for oral administration in vitro and in vivo. Asian Journal of Pharmaceutical Sciences, 2017, 285-291.

  8. Xiaopeng Han, Zhenbao Li, Jin Sun et al. Stealth CD44-targeted hyaluronic acid supramolecular nanoassemblies for doxorubicin delivery: probing the effect of uncovalent pegylation degree on cellular uptake and blood long circulation. Journal of controlled release, 2014, 197:29-40.

  9. Mengxiong Di, Zhenbao Li, Qikun Jiang et al. A rapid and sensitive supercritical fluid chromatography/tandem mass spectrometry method for detection of ezetimibein dog plasma and its application in pharmacokinetic studies J Chromatogr B Analyt Technol Biomed Life Sci, 2018, 177-182.

3年的代表性专利:

  1.  PEG化维甲酸及其自组装胶束在药物传递中的应用-201410714635.8;104399084B-已授权)。

  2. 主动定制白蛋白冕的药物传递载体及其在药学中的应用-201810151365.2(在审中)。

  3. 主动定制载脂蛋白E的药物传递载体及其在药学中的应用-201810626361.5(在审中)。

3年的获奖情况:

  1. 2018-至今:“第五届亚洲药剂学论坛” ——研究生论坛三等奖,辽宁省优秀毕业生。

  2. 2016-2017学年度:共青团优秀团员,德传奖学金,优秀研究生干部,FMC奖学金,沈阳市优秀研究生,华润三九企业奖学金。