导师简介―胡江苗

发布者:刘芳 发布时间:2016-11-06 浏览次数:

 

姓名:胡江苗

学科:药用植物化学

电话:+86-871-65223264;手机:+86-15887211981

传真:+86-871-65223261

电子邮件:hujiangmiao@mail.kib.ac.cn

通讯地址:云南省昆明市蓝黑路132号,邮编:650201

简历:

1998.9 2002.7, 安徽中医药大学药学院中药学专业学习,学士。

2002.9 2007.6, 中科院昆明植物所植化重点室植物化学专业学习,师从周俊研究员,硕士,博士。

2007.7 2009.12, 中科院昆明植物所植化重点室助理研究员。

2010.1 今, 中科院昆明植物所植化重点室副研究员。

2013年,遴选为中科院昆明植物所药物化学方向硕士研究生导师。

2015年,云南省中青年学术技术带头人后备人才。

研究领域:药用植物资源化学。

开展石斛、天麻等兰科部分药用植物的化学药理学研究;开展高活性天然产物结构修饰与活性跟踪研究。

近三年代表性论文 (通讯作者)

1. Zhen-Hua Liu,Bo Hou, Liu Yang, Rui-Jing Ma, Jin-Yu Li, Jiang-Miao Hu and Jun Zhou. Iridoids and bis-iridoids from Patrinia scabiosaefolia. RSC advance, 2017, 7: 24940-24949.

2. Zhen-Hua Liu, Rui-Jing Ma, Liu Yang, Jin-Yu Li, Bo Hou, Jiang-Miao Hu, Jun Zhou. Triterpenoids and iridoids from Patrinia scabiosaefolia. Fitoterapia, 2017, 119: 130–135

3. Feng-Qing Xu, NingWang, Wei-Wei Fan, Cheng-Ting Zi, Hong-Su Zhao, Jiang-Miao Hu, Jun Zhou. Protective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell, Fitoterapia, 2016, 115, 122127

4. Rui-Jing Ma, Zhen-Hua Liu, Cheng-Ting Zi, Wei Gao, Fa-Wu Dong, Liu Yang, Jin-Yu Li, Jun Zhou, Jiang-Miao Hu. Oleanane-type triterpene saponins from Hydrocotyle nepalensis, Fitoterapia, 2016, 110, 66-71.

5. Tao-Bin He, Yan-Ping Huang, Liu yang, Ti-Ti Liu, Wan-Ying Gong, Xuan-Jun Wang, Jun Sheng, Jiang-Miao Hu. Structural characterization and immunomodulating activity of polysaccharide from Dendrobium officinale, International Journal of Biological Macromolecules, 2016, 83, 34-41

6. Fa-Wu Dong, Zhi-Kun Wu, Liu Yang, Chen-Ting Zi, Dan Yang, Rui-Jing Ma, Zhen-Hua Liu, Huai-Rong Luo, Jun Zhou, Jiang-Miao Hu. Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells, Phytochemistry, 2015, 118, 51-60.

7. Cheng-Ting Zi, Gen-Tao Li, Yan Li, Jun Zhou, Zhong-Tao Ding, Zi-Hua Jiang, Jiang-Miao Hu. Synthesis and anticancer activity of 4β-triazole-podophyllotoxin glycosides, Natural Products and Bioprospecting, 2015, 5: 83–90

8. Cheng-Ting Zi, Dan Yang, Fa-Wu Dong, Gen-Tao Li, Yan Li, Zhong-Tao Ding, Jun Zhou, Zi-Hua Jiang and Jiang-Miao Hu. Synthesis and antitumor activity of novel per-butyrylated glycosides of podophyllotoxin and its derivatives, Bioorganic & Medicinal Chemistry, 2015, 23: 1437-1446

9. Cheng-Ting Zi, Zhen-hua Liu, Gen-Tao Li, Yan Li, Jun Zhou, Zhong-Tao Ding, Jiang-Miao Hu, Zi-Hua Jiang. Design, synthesis, and cytotoxicity of per-butyrylated glycosides of 4β-triazole-podophyllotoxin derivatives. Molecules, 2015, 20(2):3255-3280

10. Fa-Wu Dong; Liu Yang; Zhi-Kun Wu; Wei Gao; Cheng-Ting Zi; Dan Yang; Huai-Rong Luo; Jun Zhou; Jiang-Miao Hu. Iridoids and sesquiterpenoids from the roots of Valeriana jatamansi Jones. Fitoterapia, 2015, 102, 27-34.

11. Dan Yang, Liang-Yan Liu, Zhong-Quan Cheng, Feng-Qing Xu, Wei-Wei Fan, Cheng-Ting Zi, Fa-Wu Dong, Jun Zhou, Zhong-Tao Ding , Jiang-Miao Hu. Five new phenolic compounds from Dendrobium aphyllum. Fitoterapia, 2015, 100, 11-18.

12. Liu Yang, Shoujin Liu, Huai-Rong Luo, Juan Cui, Jun Zhou, Xuanjun Wang, Jun Sheng, Jiangmiao Hu. Two New dendrocandins and neurite outgrowth-promoting activity from Dendrobium officinale. Journal of Asian Natural Products Research, 2015, 17 (2), 125-131.

主持项目

生物素及糖苷化修饰鬼臼毒素类似物抗肿瘤药物研发,云南省面上项目/2015FB168,项目经费:10万元。

云南省科技厅社会发展科技计划子课题,云南铁皮石斛质量标准体系制订 (2012.3-2014.6),项目经费:65 万元。

国家自然科学基金面上项目青年人才基金,几种石斛属植物与药典石斛的药学对比研究 (No: 1130800090, 2009.1-2011.12),批准金额:19万元。

中科院西部之光西部博士项目,四种石斛属植物与药典石斛的药学对比研究 (No: 292009312D11017, 2010.1-2013.6), 批准金额:10万元。


Name: Hu Jiangmiao

SubjectPhytochemistry or Chemistry of Traditional Chinese Medicine

Tel.: +86-871-5223264

Fax: +86-871-5223261

E-mailhujiangmiao@mail.kib.ac.cn

Add.: 132#, Lanhei Road, Kunming 650204, Yunnan, China

Experience

1998.9 2002.7 Bachelor's degree majored in Traditional Chinese Medicine in Anhui College of Traditional Chinese Medicine.

2002.9 2007.6 Doctor degree majored in phytochemistry after Prof. Zhou Jun in Kunming Institute of Botany, Chinese Academy of Science.

2007.7 2009.12 Assistant Professor, Kunming Institute of Botany, Chinese Academy of Sciences.

2010.1 Present Associate Professor, Kunming Institute of Botany, Chinese Academy of Sciences.

Research AreasNatural products and medicinal chemistry.

Representative Articles:

1. Fengqing Xu, Cong Wang, Liping Yang, Huairong Luo, Weiwei Fan, Chengting Zi, Fawu Dong, Jiangmiao Hu, Jun Zhou. C-dideoxyhexosyl flavones from the stems and leaves of Passiflora edulis Sims, Food Chemistry 2013, 136, 94-99.

2. Wei-Wei Fan, Feng-Qing Xu, Fa-Wu Dong, Xiao-Nian Li, Xiao-Yong Wei, Jun Zhou, Jiang-Miao Hu. Dendrowardols A and B, Two New Sesquiterpenoids from Dendrobium wardianum Warner. Tetrahedron Letters, 2013, 54, 1928-1930

3. Cong Wang, Feng-Qing Xu, Jian-Hua Shang, HuaiXiao, Wei-Wei Fan, Fa-Wu Dong Jiang-Miao Hu, Jun Zhou. Cycloartane triterpenoids aponins from water soluble of Passiflora edulis Sims. and their antidepressant-like effects. Journal of Ethnopharmacology, 2013, 148, 812-817.

4. Peng-Cheng Wang, Xin-Hui Ran, Huai-Rong Luo, Yi-Min Zheng, Yu-Qing Liu, Jiang-Miao Hu, Jun Zhou. Nardokanshone A, a new type of sesquieterpenoid–chalcone hybrid from Nardostachys chinensis. Tetrahedron Letters, 2013, 54, 4365-4368.

5. Cheng-Ting Zi, Feng-Qing Xu, Gen-Tao Li, Yan Li, Zhong-Tao Ding, Jun Zhou, Zi-Hua Jiang and Jiang-Miao Hu. Synthesis and Anticancer Activity of Glucosylated Podophyllotoxin Derivatives Linked via 4β-Triazole Rings. Molecules, 2013, 18, 13992-14012.

6. Cheng-Bo Li, Cong Wang, Wei-Wei Fan, Fa-Wu Dong, Feng-Qing Xu, Qin-Li Wan, Huai-Rong Luo, Yu-Qing Liu, Jiang-Miao Hu, and Jun Zhou. Chemical components of Dendrobium crepidatum and their neurite outgrowth enhancing activities. Natural Products and Bioprospecting, 2013, 3, 70-73.

7. Wei-Wei FAN, Feng-Qing XU, Fa-Wu DONG, Xiao-Nian LI, Yan LI, Yu-Qing LIU, Jun ZHOU, and Jiang-Miao HU, Dendrowardol C, a novel sesquiterpenoid from Dendrobium wardianum Warner. Natural Products and Bioprospecting, 2013, 3, 89-92.

8. Jiang-Miao Hu, Weiwei Fan, Fa-Wu Dong, Ze-Hong Miao and Jun Zhou. Chemical components of Dendrobium chrysotoxum, Chinese Journal of Chemistry 2012, 30, 1327-1330.

9. Dong, F.-W.; Luo, H.-R.; Wan, Q.-L.; Xu, F.-Q.; Fan, W.-W.; Wang, K.-J.; Li, N.; Hu, J.-M., Two new bibenzyl glucosides from Dendrobium chrysotoxum, Bullitin of the Korean Chemical Society 2012, 33, 2247-2250.

10. Hu, J.-M.; Fan, W.-W.; Zhou, L.; Zhao, Y.-X.; Zhou, J., A New Phenolic Compound from Dendrobium longicornu. Bulletin of the Korean Chemical Society 2010, 31 (10), 3025-3026.

11. Hu, J.-M.; Zhao, Y.-X.; Chen, J.-J.; Miao, Z.-H.; Zhou, J., A new spongilipid from the freshwater sponge Spongilla lacustris. Bulletin of the Korean Chemical Society 2009, 30 (5), 1170-1172.

12. Hu, J.-M.; Zhao, Y.-X.; Miao, Z.-H.; Zhou, J., Chemical components of Dendrobium polyanthum. Bulletin of the Korean Chemical Society 2009, 30 (9), 2098-2100.

13. Hu, J.-M.; Chen, J.-J.; Yu, H.; Zhao, Y.-X.; Zhou, J., Two novel bibenzyls from Dendrobium trigonopus. Journal of Asian Natural Products Research 2008, 10 (7), 647-651.

14. Hu, J.-M.; Chen, J.-J.; Yu, H.; Zhao, Y.-X.; Zhou, J., Five new compounds from Dendrobium longicornu. Planta Medica 2008, 74 (5), 535-539.