导师简介-贾晓益

发布者:刘芳 发布时间:2018-03-22 浏览次数:

个人简历

贾晓益,女,博士,副教授,药理学专业硕士生导师,安徽中医药大学药学院中药药理系教师,主要从事炎症免疫性疾病的机制和中药药物靶点相关研究。近年来主持国家自然科学基金青年基金项目1项,安徽省高校自然科学基金资助项目2项、安徽中医药大学自然基金1项,参与多项国家自然科学基金、省自然科学基金等课题研究,发表学术论文20余篇。

正在承担的科研项目:

1)安徽省高等学校自然科学研究项目:前列腺素受体及其信号对关节炎树突状细胞的调节作用及机制(KJ2015A317),2015/01-2017/126万;

2)安徽中医药大学校级自然科学研究项目:黄柏-苍术药对改善类风湿性关节炎的药效物质基础研究(2016zr010),2016/01-2017/121万;

3)国家自然基金青年项目:基于EP4-cAMP-PKA信号通路调控树突状细胞功能探讨二妙散对佐剂性关节炎的作用机制(81603362),2017/01-2019/1217

5年发表的主要论文:

(1) Jia X(贾晓益), Wei F, Sun X, Chang Y, Xu S, Yang X, Wang C, Wei W*. CP-25 attenuates the inflammatory response of fibroblast-like synoviocytes co-cultured with BAFF-activated CD4+ T cells. J Ethnopharmacol. 2016, 189:194-201.

(2) Jia XY(贾晓益), Chang Y, Sun XJ, Dai X, Wei W*, The role of prostaglandin E2 receptor signaling of dendritic cells in rheumatoid arthritis, Int Immunopharmacol, 2014, 23(1):163-169.

(3) Jia XY(贾晓益), Chang Y, Sun XJ, Wu HX, Wang C, Xu HM, Zhang L, Zhang LL, Zheng YQ, Song LH*, Wei W*, Total glucosides of paeony inhibit the proliferation of fibroblast-like synoviocytes through the regulation of G proteins in rats with collagen-induced arthritis, Int Immunopharmacol, 2014, 18(1):1-6.

(4) Chang Y, Jia X(贾晓益), Wei F, Wang C, Sun X, Xu S, Yang X, Zhao Y, Chen J, Wu H, Zhang L, Wei W. CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage. Sci Rep. 2016; 6:26239.

(5) Zhou P, Yang X, Jia X(贾晓益), Yu J, Asenso J, Xiao F, Wang C, Wei W*, Effect of 6'-acetylpaeoniflorin on dinitrochlorobenzene-induced allergic contact dermatitis in BALB/c mice, Immunol Res, 2016; 64(4):857-68.

(6) Dai X, Wu Y, Jia X(贾晓益), Chang Y, Wu H, Wang C, Chen H, Chen W, Huang Q, Wei W*, hIgD promotes human Burkitt lymphoma Daudi cell proliferation by accelerated G1/S transition via IgD receptor activity, Immunol Res, 2016; 64(4):978-87.

(7) Wei F, Xu S, Jia X(贾晓益), Sun X, Yang X, Wei W*, Chang Y*, BAFF and its receptors involved in the inflammation progress in adjuvant induced arthritis rats, Int Immunopharmacol, 2016, 31:1-8.

(8) Chang Y, Jia X(贾晓益), Sun X, Xu S, Wu Y, Zhang L, Wei W*, APRIL promotes proliferation, secretion and invasion of fibroblast-like synoviocyte from rats with adjuvant induced arthritis, Mol Immunol, 2015, 64(1):90-98.

(9) Chang Y, Sun X, Jia X(贾晓益), Xu S, Wei F, Yang X, Wei W*, Expression and effects of B-lymphocyte stimulator and its receptors in T cell-mediated autoimmune arthritis, Int Immunopharmacol, 2015, 24(2):451-457.

(10) Dai X, Wang LW, Jia XY(贾晓益), Chang Y, Wu HX, Wang C, Wei W*, Paeoniflorin regulates the function of human peripheral blood mononuclear cells stimulated by rhIL-1β by up-regulating Treg expression, Immunopharmacol Immunotoxicol, 2015, 37(3):252-257.

(11) Wu H, Chen J, Wang Q, Jia X(贾晓益), Song S, Yuan P, Liu K, Liu L, Zhang Y, Zhou A, Wei W*, Ginsenoside metabolite compound K attenuates inflammatory responses of adjuvant-induced arthritis rats, Immunopharmacol Immunotoxicol. 2014, 36(2): 124-129.

(12) 贾晓益,常艳,张磊,魏伟*, 白芍总苷对胶原性关节炎滑膜组织 MAPKs 信号通路的调控作用, 安徽医科大学学报, 2013, 489):1067 ~ 1070.

联系方式:

E-mailjiaxiaoyi78@126.com