韦韬,男,校聘研究员,硕士研究生导师。
一、个人简历
韦韬,男,安徽省安庆市太湖县人,校聘研究员,理学博士,理学博士后。主持国家自然科学基金青年项目、安徽中医药大学高层次人才支持计划项目、安徽省教育厅重点项目和中央高校基本科研项目各1项。以第一作者发表SCI论文8篇,参与发表SCI论文多篇。
二、主持科研项目情况
1. 安徽省教育厅重点科研项目:基于CRISPR/Cas9技术的灵芝酸代谢途径调控研究(2023AH050823)在研
2. 安徽中医药大学人才支持计划项目:灵芝酸生物合成相关转录因子的筛选及其调控机理研究(2023rcZD001)在研
3. 国家自然科学基金青年项目:基于CRISPR/Cas9技术的大豆AHAS基因定点修饰及除草剂抗性研究(22007050)结题
4. 中央高校基本科研项目:基于CRISPR/Cas9技术的大豆基因定点修饰及抗除草剂研究(63191320)结题
三、代表性学术论文
1. Tao Wei, Linjian Jiang, Xiang You, Pengyu Ma, Zhen Xi and Ning Ning Wang (2023) Generation of Herbicide-Resistant Soybean by Base Editing. Biology 12: 741.
2. Tao Wei, Xin Wen, Congwei Niu, Sijing An, Dawei Wang, Zhen Xi and Ning Ning Wang (2022) Design of Acetohydroxyacid Synthase herbicide-resistant germplasm through MB-QSAR and CRISPR/Cas9-mediated base-editing approaches. Journal of Agricultural and Food Chemistry 70: 2817−2824.
3. Tao Wei, Kejun Deng, Yonghong Gao, Li Chen, Wenqin Song, Yong Zhang, Chunguo Wang and Chengbin Chen (2020) SmKSL overexpression combined with elicitor treatment enhances tanshinone production from Salvia miltiorrhiza hairy roots. Biochemical Engineering Journal 158: 107562.
4. Tao Wei, Yonghong Gao, Kejun Deng, Lipeng Zhang, Meiling Yang, Xiaopei Liu, Caiyan Qi, Chunguo Wang, Wenqin Song, Yong Zhang and Chengbin Chen (2019) Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering. Plant Methods 15:53.
5. Tao Wei, Kejun Deng, Hongbin Wang, Lipeng Zhang, Chunguo Wang, Wenqin Song, Yong Zhang and Chengbin Chen (2018) Comparative Transcriptome Analyses Reveal Potential Mechanisms of Enhanced Drought Tolerance in Transgenic Salvia Miltiorrhiza Plants Expressing AtDREB1A from Arabidopsis. International Journal of Molecular Sciences 19:827.
6. Tao Wei, Kejun Deng, Qingxia Zhang, Yonghong Gao, Yu Liu, Meiling Yang, Lipeng Zhang, Xuelian Zheng, Chunguo Wang, Zhiwei Liu, Chengbin Chen and Yong Zhang (2017) Modulating AtDREB1C expression improves drought tolerance in Salvia miltiorrhiza. Frontiers in Plant Science 8:52.
7. Tao Wei, Kejun Deng, Dongqing Liu, Yonghong Gao, Yu Liu, Meiling Yang, Lipeng Zhang, Xuelian Zheng, Chunguo Wang, Wenqin Song, Chengbin Chen and Yong Zhang (2016) Ectopic Expression of DREB Transcription Factor, AtDREB1A, Confers Tolerance to Drought in Transgenic Salvia miltiorrhiza. Plant and Cell Physiology 57:1593-1609.
8. Tao Wei, Kejun Deng, Yonghong Gao, Yu Liu, Meiling Yang, Lipeng Zhang, Xuelian Zheng, Chunguo Wang, Wenqin Song, Chengbin Chen and Yong Zhang (2016) Arabidopsis DREB1B in transgenic Salvia miltiorrhiza increased tolerance to drought stress without stunting growth. Plant Physiology and Biochemistry 104:17-28.
四、主要研究方向
1. 中药资源生物活性成分代谢调控
2. 中药活性成分防治阿尔茨海默症作用机制研究
五、联系方式
电子邮箱:weitao88888@ahtcm.edu.cn; weitao88888@163.com.