王维胜，复旦大学脑科学转化研究院/中山医院，双聘研究员，博士生导师。博士毕业于中科院上海药物研究所，于2013年至2021年分别在加州大学欧文分校和洛杉矶分校进行博士后训练。2021年8月加入复旦大学脑科学转化研究院，担任课题组长，研究员。主要关注负性情绪的神经环路机制，以及情景记忆的神经环路与分子机制研究。在Nature Neuroscience, Neuron，Molecular Psychiary, eLife, Journal of neuroscience, Cerebral Cortexd等神经科学重要杂志共发表文章20篇，其中第一作者文章11篇。
科研项目
1. 美国脑与行为研究基金会项目，“Dissection of circuits that control panic related behaviors” (2019-2021)；
2. 国家自然科学面上项目，“中缝背核-脑干神经环路调控惊恐情绪的作用机制”（2023—2026）；
3. 脑科学与类脑研究重大项目，“恐惧情绪的神经环路机制研究”（2022-2025）。
发表论文
1. Wang W#, Schuette PJ#, Nagai J, Tobias BC, Reis FMCV, Ji S, Lima MAX, La-Vu MQ, Pereira SM, Chakerian M, Leonard S, Lin L, Severino A, Cahill C, Canteras NS, Khakh BS, Kao J, Adhikari A*. (2021) Coordination of Escape and Spatial Navigation Circuits Orchestrate Versatile Flight from Threats. Neuron. 109(11):1848-1860 (Featured Article).
2. Wang W#, Schuette PJ#, La-Vu MQ, Tobias BC, Reis FMCV, Ji S, Sehgal M, Canteras NS, Khakh BS, Wager TD, Kao JC, Adhikari A*.（2021）Dorsal premammillary hypothalamic projection to periaqueductal gray controls escape vigor. eLife. 10:e69178
3. Wang W#, Cox BM#, Jia Y, Le A. A, Jung KM, Hou J, Piomelli D, Gall CM, Lynch G (2018). Treating a novel plasticity defect rescues episodic memory in Fragile X model mice. Molecular Psychiatry, 23 (8):1798-1806.
4. Wang W, Jia Y, Pham DT, Jung KM, Cox CD, Rumbaugh G, Piomelli D, Gall CM, Lynch G (2018). Atypical endocannabinoid signaling initiates a new form of memory-related plasticity at a cortical input to hippocampus. Cerebral Cortex. 28(7):2253-2266.
5. Wang W, Le A, Hou J, Levin ER, Lynch G, Gall CM (2018). Memory-related synaptic plasticity is sexually dimorphic in rodent hippocampus.J Neurosci. 38(37):7935-7951. (Featured Article; recommended in F1000).
6. Wang W#, Ju YY#, Zhou Qin#, Tang JX, Li M, Zhang L, Kang S, Chen ZG, Ji H, Xu L, Liu JG (2017).The small GTPase Rac1 contributes to extinction of aversive memories of drug withdrawal by facilitating GABAA receptor endocytosis in the vmPFC. J Neurosci. 37(30):7096-7110. (Featured Article).
7. Wang W#, Trieu BH#, Palmer LC, Jia Y, Pham DT, Jung KM, Gall CM, Piomelli D, Lynch
G. (2016) A primary cortical input to hippocampus expresses a pathway-specific and endocannabinoid-dependent form of Long-Term Potentiation. eNeuro. 8;3(4). pii: ENEURO.0160-16.2016. (Featured by Neuronline)
8. Wang W, Kantorovich S, Babayan AH, Hou B, Gall CM, Lynch G. (2016). Estrogen's effects on excitatory synaptic transmission entail integrin and TrkB transactivation and depend upon β1-integrin function. Neuropsychopharmacology. 41(11):2723-32.
9. Chen ZG#, Liu X#, Wang W#, Geng F, Gao J, Gan CL, Chai JR, He L, Hu G, Zhou H, Liu JG. (2016). Dissociative role for dorsal hippocampus in mediating heroin self-administration and relapse through CDK5 and RhoB signaling revealed by proteomic analysis. Addiction Biology. 22 (6):1731-1742.
10. Wang W#, Chen ZG#, Liu WT, Chi ZQ, He L, Liu JG (2015). Dorsal hippocampal NMDA receptor blockade impairs extinction of naloxone-precipitated conditioned place aversion in acute morphine-treated rats by suppressing ERK and CREB phosphorylation in the basolateral amygdala. Br. J. Pharmacol..172(2):482-91.
11. Wang W#, Kang S#, Liu WT, Li M, Liu Y, Yu C, Chen J, Chi ZQ, He L, Liu JG (2012). Extinction of aversive memories associated with morphine withdrawal requires ERK-mediated epigenetic regulation of brain-derived neurotrophic factor transcription in the rat ventromedial prefrontal cortex. J Neurosci. 32 (40), 13763•13775. ( Featured by Science Times).
研究方向
负性情绪以及情景记忆的神经环路与分子机制研究
联系方式：
weishengw@fudan.edu.cn
