一、个人简历
洪燕,女,医学硕士,副教授,中西医结合基础专业硕士生导师。中国解剖学会委员,安徽省药理学会委员;Journal of Ethnopharmacology,Evidence-Based Complementary and Alternative Medicine和中药药理与临床等杂志特邀审稿专家。
二、教学科研情况
主要承担本科生《组织胚胎学》、《细胞生物学》和《优生优育学》等课程,并从事肝纤维化发病机制及中药干预研究以及中药药效物质基础研究。近年以通讯或第一作者发表科研论文10余篇,期中SCI收录5篇,主持高校自然科学基金重点项目等课题2项,参与安徽省级自然科学基金等课题4项。
三、近五年来主持参与科研项目情况
1.安徽省教育厅, 高校自然科学基金重点项目, KJ2021A0601, 肝窦内皮细胞源外泌体靶向调控HSC血管新生相关信号通路抗肝纤维化及重楼皂苷的干预作用研究, 2021/10-2023/12, 6万元, 主持,在研
3.安徽中医药大学自然科学重点研究项目,2020zrzd05,LSEC源Exosomes靶向HSC的Ras/Raf/ MEK/ERK 信号通路抑制肝纤维化血管新生及重楼皂苷的干预作用,2020/06 -2022/12,3.0万元,主持,在研
2.安徽省自然科学基金,2108085MH313,姜炮制-配伍的“性-效-物质基础”转变规律研究,2021/9-2023/12,12万元,参与
4.安徽省教育厅, 高校自然科学基金重点项目, KJ2022A0704,,复方姜酚调控PI3K-AKT-mTOR 信号通路诱导肝癌细胞铁死亡的研究,2022/09-2024/09,10万元,在研,参与;
四、近年来发表有代表性学术论文、专著或教材(限5篇)
1.Yu Jiang, Chao Bu, Lanlan Fan, Gang Cao, Li Sun, Rodney J.Y. Ho, Deling Wu, Shuangying Gui, Yanquan Han*, Yan Hong*. Screening for the extracorporeal coagulation activity quality markers (Q-markers) of dried and stir fried ginger[J]. Arab J Chem. (2022) 15, 104151.
2. Lanlan Fan, Congwen Gu, Yu Jiang, Gang Cao, Li Sun, Rodney J.Y. Ho, Deling Wu, Yanquan Han*, Yan Hong*. Screening of different chemical components of sedative and hypnotic effects of Ziziphi Spinosae Semen before and after frying and determination of the Q-Marker[J]. J Chromatogr B. 2022; 1207:123349.
3. Shan Ran, Fangfang Sun, Yan Song, Xiaoli Wang, Yan Hong* and Yanquan Han*. The Study of Dried Ginger and Linggan Wuwei Jiangxin Decoction Treatment of Cld Asthma Rats Using GC–MS Based Metabolomics[J]. Frontiers in Pharmacology, 2019, 10:1-15.
4. Yanquan Han#, Lingyu Pan#, Shan Ran,Yan Song, Fang-Fang Sun,Yong-Zhong Wang*,Yan Hong*. Rhizoma Paridis saponins ameliorates hepatic fifibrosis in rats by downregulating expression of angiogenesis-associated growth factors[J]. Molecular Medicine Reports, 2019,19(5):3548-3554.
5. Yan Hong, Yan-Quan Han*, Yong-Zhong Wang*, Jia-Rong Gao, Yu-Xin Li, Qing Liu, Lun-Zhu Xia. Paridis Rhizoma Sapoinins attenuates liver fifibrosis in rats by regulating the expression of RASAL1/ERK1/2 signalpathway[J].Journal of Ethnopharmacology,2016,192(4): 114–122.
五、联系方式
Email:hyan2003@163.com;QQ:591940167