吴清华,男,1990年4月出生,研究员,药物化学及药学专业硕士研究生导师。主要研究方向:光诊疗功能分子的设计开发及生物应用的研究,智能响应型靶向药物分子的设计开发。目前发表SCI论文60余篇,其中以第一作者或者通讯作者身份在Angew. Chem.Int. Ed., Org. Lett.,Chem. Commun.,Sci. China. Mater.,ACS Appl. Mater. Interfaces, J. Mater. Chem. B等期刊上发表SCI论文13篇。作为主要完成人参与国家自然科学基金重点/面上项目及安徽省杰出青年项目7项。
一、近3年来主持科研项目情况
1、安徽省自然科学青年基金(2108085QB81),主持,在研;
2、安徽省教育厅安徽省高校自然科学研究重点项目(KJ2020A0071),主持;在研;
3、安徽省博士后科学基金,主持,在研;
4、安徽中医药大学人才支持计划重点项目,主持,在研。
二、近3年来发表有代表性学术论文
1. Guo, X.; Yang, J.; Li, M.; Zhang, F.; Bu, W.; Li, H.; Wu, Q.;*(Corresponding author) Yin, D.; Jiao, L.; Hao, E. Unique Double Intramolecular and Intermolecular Exciton Coupling in Ethene-Bridged aza-BODIPY Dimers for High-Efficiency Near-Infrared Photothermal Conversion and Therapy. Angew. Chem.Int. Ed. 2022, e202211081. (自然指数期刊, Top期刊,中科院1区)
2. Guo, X.; Tang, B.; Wu, Q.;*(Corresponding author) Bu, W.; Zhang, F.; Yu, C.; Jiao, L.; Hao, E. Engineering BODIPY-based Near-Infrared Nanoparticles with Large Stokes Shifts and Aggregation-Induced Emission Characteristics for Organelle Specific Bioimaging. J. Mater. Chem. B, 2022, 10, 5612-5623. (Top期刊, 中科院1区)
3. Kang, Z.; Wu, Q.;*(Corresponding author) Zhou, X.; Gong, Q.; Lv, F.; Hao, E.; Jiao, L. FeCl3-Promoted Regioselective Synthesis of BODIPY Dimers through Oxidative Aromatic Homocoupling Reactions. Chem. Commun. 2021, 57, 9886-9889. (自然指数期刊, Top期刊,中科院1区)
4. Zhu, Y.;# Wu, Q.;# (# contributed equally); Chen, C.; Yang, G.; Gao, Y.; Jiao, L.; Hao, E.; Zhang, W. A NIR-Absorbing Superoxide Radical and Hyperthermia Photogenerator via Twisted Donor-Acceptor-Donor Molecular Rotation for Hypoxic Tumor Eradication. Science China Materials. 2021, 64, 3101-3113. (Top期刊, 中科院1区)
5. Wu, Q.; Jia, G.; Tang, B.; Guo, X.; Wu, H.; Yu, C.; Hao, E.; Jiao, L. Conformationally Restricted Directly Linked BisBODIPYs as Highly Fluorescent Near-Infrared Absorbing Dyes. Org. Lett. 2020, 22, 9239-9243. (自然指数期刊, Top期刊,中科院1区)
6. Wu, Q.; Kang, Z.; Gong, Q.; Guo, X.; Wang, H.; Wang, D.; Jiao, L.; Hao, E. Strategic Construction of Ethene-Bridged BODIPY Arrays with Absorption Bands Reaching the Near-Infrared II Region. Org. Lett. 2020, 22, 7513-7517. (自然指数期刊, Top期刊,中科院1区)
7. Wu, Q.;# Zhu, Y.;# (# contributed equally) Fang, X.; Hao, X.; Jiao, L.; Hao, E.; Zhang, W. Conjugated BODIPY Oligomers with Controllable Near-Infrared Absorptions as Promising Phototheranostic Agents through Excited-State Intramolecular Rotations. ACS Appl. Mater. Interfaces 2020, 12, 47208-47219. (Top期刊, 中科院1区)
三、指导研究生情况
现指导研究生3名。
课题组招收药物化学及药学专业硕士研究生。
常年欢迎对药学/化学科学有兴趣、具有自我激励品质的本科生。
四、联系方式
电子邮箱:qinghuaw@ahtcm.edu.cn
办公地址:药学院136
欢迎具有药学、化学及生物学背景的你加入课题组!