导师简介-汪永忠

发布者:研究生院 发布时间:2024-05-09 浏览次数:

一、个人简历

汪永忠,男,197012月出生,主任药师,硕士研究生导师,安徽中医药大学第一附属医院药学部副主任,长期从事医院临床药学教学、科研和药事管理工作。主要研究方向:中药新药研发及其靶向治疗支气管哮喘疾病的研究。

二、教学科研情况(包括主要在研课题、获奖成果等)

1、科研项目

[1] 安徽省卫生健康科研重点项目,甲基化转移酶METTL3介导p53 m6A水平诱发气道平滑肌细胞自噬抑制支气管哮喘发病及阳和平喘颗粒的干预作用,2023.12-2026.1140万元,在研,主持。

[2] 安徽省高等学校科学研究项目,p53/SLC7A11/GPX4 信号轴调控气道平滑肌细胞铁死亡诱导支气管哮喘发病及阳和平喘颗粒的干预作用,2023.8-2025.710万元,在研,参与。

2、获奖成果

国家发明专利,《一种智脑胶囊指纹图谱建立方法及质量评价方法》,2022年,排名第二。

三、论著情况(包括代表性论文、专著、教材)

1、代表性论文

[1] Lingyu Pan, Bang Fu, Chunxia Gong, Yehong Sun Xianchun Duan, Yanquan Han, Jijun Chu*, Yongzhong Wang*. Analysis of global gene expression using RNA-sequencing reveals novel mechanism of Yanghe Pingchuan decoction in the treatment of asthma. BMC Pulm Med. 2024;24:137.

[2] Chunxia Gong, Lingyu Pan, Yeke Jiang, Yehong Sun Yanquan HanDianlei Wang, Yongzhong Wang*. Investigating the mechanism of action of Yanghe Pingchuan Granule in the treatment of bronchial asthma based on bioinformatics and experimental validation. Heliyon. 2023;9:e21936.

[3] Lingyu Pan, Chunxia Gong, Yan Chen, Yeke Jiang, Yehong Sun, Bangfu He, Xianchun Duan, Yanquan Han, Yongzhong Wang*. Yanghe Pingchuan granules mitigates oxidative stress and inflammation in a bronchial asthma rat model: role of the IKK/IκB/NF-κB signalling pathway. Ann Med Surg (Lond). 2023;86:212-218.

[4] Yuan Sun, Hui Jiang, Lingyu Pan, Yanquan Han, Yan chen, Yeke Jiang, Yongzhong Wang*. LncRNA OIP5-AS1/miR-410-3p/Wnt7b axis promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via regulating the Wnt/β-catenin pathway. Autoimmunity. 2023;56:2189136.

[5] Lingyu Pan, Chunxia Gong, Yehong Sun, Yeke Jiang, Xianchun, Yanquan Han, Yongzhong Wang*. Induction mechanism of ferroptosis: A novel therapeutic target in lung disease. Front Pharmacol. 2022;13:0-12.

[6] Lingyu Pan, Yan Chen, Yeke Jiang, Yehong Sun, Yanquan Han, Yongzhong Wang*. Yanghe Pingchuan Granules Alleviate Airway Inflammation in Bronchial Asthma and Inhibit Pyroptosis by Blocking the TLR4/NF-κB/NRLP3 Signaling Pathway. Mediators Inflamm. 2022;2022:1-9.

[7] Lingyu Pan, Yuan Sun, Hui Jiang, Yan Chen, Yeke Jiang, Yanquan Han, Yongzhong Wang*. Total Saponins of Radix Clematis Regulate Fibroblast-Like Synoviocyte Proliferation in Rheumatoid Arthritis via the LncRNA OIP5-AS1/MiR-410-3p/Wnt7b Signaling Pathway. Evid Based Complement Alternat Med. 2022;2022:8393949.

四、研究生带教情况

现独立或联合培养硕士研究生9

五、联系方式

电话:0551-62838556;  

邮箱:wyzhmail@163.com