一、个人简历
储俊，男，1979年11月出生，安徽潜山市人，中共党员，生物化学及分子生物学专业博士，哈佛大学访问学者，安徽中医药大学新安医学教育部重点实验室现代实验技术教研室主任，副教授，硕士生导师，安徽省生物化学及分子生物学学会理事。
教育经历：
2009/09 – 2014/01，中国科技大学，生命科学学院，博士，导师: 周丛照/陈宇星
2003/09–2006/07，浙江大学，生命科学学院，硕士，导师: 吴平
1999/09–2003/06，中国科技大学，学士
科研与学术工作经历：
1、2019/12 - 2021/03，Harvard University Division of Medical Sciences,
Dana-Farber Cancer Institute, 访问学者，导师: 刘晓乐 Xiaole Shirley Liu
2、2016/11 - 至今， 安徽中医药大学, 副教授
3、2014/07 - 2016/10，安徽中医药大学, 讲师
二、教学科研情况（包括主要在研课题、获奖成果等）
1. 安徽省高等学校科学研究项目（自然科学类），2023AH050835，葛根芩连汤通过Nrf2抑制铁死亡改善2型糖尿病肝损伤的分子机制研究，在研， 主持
2. 棉花生物育种与综合利用全国重点实验室开放课题，CB2023A25，基于UPLC-QTOF-MS研究棉花花瓣总黄酮干预阿尔兹海默症的活性成分，在研，主持
3. 茶树生物学与资源利用国家重点实验室开放课题重点项目，SKLTOF20210101，黄大茶介导TGF-β/Smad3 信号通路缓解糖尿病大鼠肾脏纤维化的分子机制,在研，主持
4. 安徽省教育厅2020年高校自然科学重点项目，KJ2020A0383，基于“肠-菌”互作研究SIRT1通路在葛根芩连汤防治糖尿病肾病的分子机制,结题，主持
5. 安徽省高校优秀拔尖人才培育国外访学项目, gxgwfx2019027,结题，主持
6. 安徽省2017年公益性技术应用研究联动计划，1704f0804032，基于转录组学对新藤黄酸、蛇床子素联合阿霉素应用逆转乳腺癌多药耐药的作用机制研究，结题，主持
7. 中国农业科学院棉花国家重点实验室开放课题项目，CB2018A09，棉花花总黄酮干预阿尔兹海默症分子机制研究,结题，主持
8. 国家自然科学基金面上项目，81774189，基于“痰瘀阻络说”研究“搜剔络道痰瘀同治”对DCM大鼠心肌AGEs及所致病变的干预作用，结题，参加 (排名第二）
9. 国家自然科学基金面上项目，81673650，基于PTEN-PI3K/AKT信号通路调控细胞自噬研究新藤黄酸逆转乳腺癌耐药的作用机制，结题，参加
10. 国家自然科学基金面上项目，81573670，基于TLR/MyD88/NF-kB受体信号通路和NALP3炎性体研究萆薢总皂苷治疗痛风性关节炎的机制, 2016/01-2019/12，68万元，结题，参加
11. 安徽省教育厅高校优秀青年人才支持计划重点项目，gxyqZD2016139，基于RNA-seq对蛇床子素合成途径中蛇床子关键基因的功能研究，结题，主持
三、论著情况（包括代表性论文、专著、教材）
(1) Zhangxin Jia,c1, Chenxu Zhanga,c1, Jingjing Yuana,d, Qing Hea,c, Xinyu Zhanga,c, Dongmei Yanga,c, Na Xub* and Jun Chua,d,e*. Is there a causal association between gestational diabetes mellitus and immune mediators? A bidirectional mendelian randomization analysis. Frontiers in Endocrinology. Accepted. (IF:5.2 Q1 医学2区)
(2) Zhangxin Jia,c1, Chenxu Zhanga,c1, Jingjing Yuana,d, Qing Hea,c, Xinyu Zhanga,c, Dongmei Yanga,c, Na Xub* and Jun Chua,d,e*. Predicting the immunity landscape and prognosis with an NCLs signature in liver hepatocellular carcinoma. PLOS ONE. Accepted. (IF:3.7 Q2 综合期刊3区)
(3) Xiang-Yu Wang, You-Mei Lin, Xiao-Yan Sun, Ya-Qian Wu, Hui Miao, Jun Chu *, Tian-Wen Bai *, Ying-Long Fu *. A lysosomal targeted fluorescent probe based on BODIPY for monitoring NO in living cells and zebrafish imaging [J]. Sensors and Actuators B: Chemical, Volume 383,2023,133592, https://doi.org/10.1016/j.snb.2023.133592.(co-response author) (IF:8.4, Q1 化学1区 Top)
(4) Dong J, Zhou K, Ge X, and Xu, Na and Wang, Xiao and He, Qing and Zhang, Chenxu and Chu Jun * and Li, Qinglin *. Effects of Extraction Technique on the Content and Antioxidant Activity of Flavonoids from Gossypium Hirsutum linn. Flowers[J]. Molecules, 2022, 27(17): 5627. doi: 10.3390/molecules27175627. (IF:4.6, Q2 化学2区 Top)
(5) Yang Y, Huang H, Cui Z, Chu J *, Du G *. UPLC–MS/MS and Network Pharmacology-Based Analysis of Bioactive Anti-Depression Compounds in Betel Nut. Drug Des Devel ther.2021;15:4827-4836. (IF:4.8, (IF:4.8, Q2 医学3区)
(6) Xiaoqing Wang, Collin Tokheim,Shengqing Stan Gu，Binbin Wang,Qin Tang,Yihao Li,Nicole Traugh,Zexian Zeng ,Yi Zhang,Ziyi Li,Boning Zhang, Jingxin Fu,Tengfei Xiao ,Wei Li ,Clifford A Meyer , Jun Chu ,Peng Jiang ,Paloma Cejas ,Klothilda Lim ,Henry Long ,Myles Brown ,X Shirley Liu .In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target. Cell. 2021 Oct 14;184(21)：5357-5374.e22. (IF:64.5 Q1 生物学1区 Top)
(7) Collin Tokheim1,2,11, Xiaoqing Wang1,2,3,11, Richard T. Timms4,5,11,†, Boning Zhang1,2,3,Elijah L. Mena4,5, Binbin Wang6,Cynthia Chen7, Jun Ge6, Jun Chu8,Wubing Zhang6, Stephen J. Elledge5,9,*, Myles Brown3,10,*, X. Shirley Liu1 Systematic Characterization of Mutations Altering Protein Degradation in Human Cancers, Molecular Cell, Mol Cell. 2021 Mar 18;81(6):1292-1308.e11. doi: 10.1016/j.molcel.2021.01.020. Epub 2021 Feb 9. PMID: 33567269. (IF:16.0 Q1 生物学1区 Top)
(8) Na Xu#，Jun Chu#，Rongrong Dong, Fengjuan Lu,Xinfeng Zhang, Min Wang, Ying Shen, Zhongwen Xie, Chi-Tang He, CS Yang, Yijun Wang, Xiaochun Wan*Yellow Tea Stimulates Thermogenesis in Mice Through Heterogeneous Browning of Adipose Tissues, Molecular Nutrition and Food Research, 2021 Jan;65(2):e2000864. doi: 10.1002/mnfr.202000864. Epub 2021 Jan 7. PMID: 33258303. (IF:5.2 Q1 农林科学2区)
(9) Xiao Wang, Na Xu, Qinglin Li, Shengqi Chen, Hui Cheng , Mo Yang , Ting Jiang, Jun Chu *, Xiaojing Ma and Dengke Yin,Lactonic Sophorolipids-induced apoptosis in human HepG2 cells through the Caspase-3 pathway, Applied Microbiology and Biotechnology, (2021) 105:2033–2042 (IF:5.0 Q1 工程技术2区 Top)
(10) Ting Jiang, Hui Cheng, Jingjing Su, Xuncui Wang, Qiaoxue Wang, Jun Chu*, Qinglin Li*,Gastrodin protects against glutamate-induced ferroptosis in HT-22 cells through Nrf2/HO-1 signaling pathway,Toxicology in Vitro,Volume 62,2020,104715, https://doi.org/10.1016/j.tiv.2019.104715 (IF:3.2 Q2 医学3区)
(11) Jun Chu, Chengxu Liu, Rui Song, Qinglin Li*. Ferrostatin-1 protects HT-22 cells from oxidative toxicity. Neural Regen Res. 2020 Mar; 15(3): 528–536 (IF:6.1 Q1/Q2 医学2区)
(12) Fei Ke, Mengran Zhang, Nianqiao Qin, Gege Zhao, Jun Chu, Xiaochun Wan*.Synergistic antioxidant activity and anticancer effect of green tea catechin stabilized on nanoscale cyclodextrin-metal organic frameworks. Journal of Materials Science, 2019, 54: 10420. https://doi.org/10.1007/s10853-019-03604-7 (IF:4.5 Q2 材料科学3区)
(13) Na Xu#, Jun Chu# , Min Wang, Ling Chen, Liang Zhang, Zhong-Wen Xie, Jin-Song Zhang, Chi-Tong Ho, Da-Xiang Li*, Xiao-Chun Wan*, Large Yellow Tea Attenuates Macrophage- Related Chronic Inflammation and Metabolic Syndrome in High-Fat Diet Treated Mice, Journal of Agriculture Food Chemistry. 2018, 66(15):3823-3832. (IF:6.1 Q1 农林科学1区 Top)
(14) Hua, X., Wu, Y.-J., Zhang, X., Cheng, S., Wang, X., Chu, J. * and Huang, Q*. (2018). Analysis on Ambient Volatile Organic Compounds and their Human Gene Targets. Aerosol and Air Quality Research 18, 2654-2665. (IF:4.0 Q2 环境科学与生态学4区)
(15) Jun Chu, Wei-Fang Li,Wang Cheng,Mo Lu,Ke-Hai Zhou,He-Qin Zhu,Fu-Guang Li,Cong-Zhao Zhou*, Comparative analyses of secreted proteins from the phytopathogenic fungus Verticillium dahliae in response to nitrogen starvation, Biochimica Biophys Acta-proteins and proteomics, 2015 , 1854( 5): 437-448. (IF:3.2 Q2/Q3 生物学3区)
(16) Yi Liao, Miao Miao LIU,Qing Ling Li, Jun Chu, Jing Jing Su, Jia Wen WU*, Cloning, Expression, and Characterization of Three Ribosomal Protein S13 Genes In Sophora flavescens ,Bioscience Journal, 2018,34(5):1379-1391. (IF:0.5 Q4 农林科学4区)
(17) Wang Cheng#, Lei Wang#,Yong-Liang Jiang,Xiao-Hui Bai, Jun Chu, Qiong Li,Ge Yu,Qiu-Ling Liang,Cong-Zhao Zhou*,andYu-Xing Chen*, Structural Insights into the Substrate Specificity ofStreptococcus pneumonia β(1,3)-Galactosidase BgaC, Journal of Biology Chemistry, 2012, 287(27): 22910-22918. (IF:4.8 Q2)
(18) Xiao-Peng Qi, Zhong-Chang Wu, Jin-Hui Li, Xiao-Rong Mo, Shi-Hua Wu, JunChu, Ping Wu*, AtCYT-INV1, a neutral invertase, is involved in osmotic stress-induced inhibition on lateral root growth in Arabidopsis, Plant Molecular Biology, 2007, 64(5):575-587. (IF:5.1 Q1/Q2 生物学2区)
(19) Li-Ming Du#, Fang-Chan Jiao#, JunChu, Gu-Lei Jin, Ming Chen, Ping Wu*, The two-component signal system in rice (Oryza sativa L.): a genome-wide study of cytokinin signal perception and transduction, Genomics, 2007, 89(6):697-707. (IF:4.4 Q2 生物学3区)
专利：
1、一种响应面法优化提取棉花鲜花总黄酮的方法(专利号：ZL 2019 1 0235997.1）
四、主要研究方向，研究生带教情况
中药复方干预糖脂代谢性疾病；已毕业研究生2人，在读8人。
五、联系方式
办公电话：0551-65169051
邮箱：chuj@ahtcm.edu.cn
