
储俊 个人简历
男,1979年出生,安徽潜山市人,中共党员,
生物化学及分子生物学专业博士,
安徽中医药大学新安医学教育部重点实验室
现代实验技术教研室主任,教授,硕士生导师,
安徽省生物化学及分子生物学学会理事。
教育经历:
2009/09 – 2014/01,中国科技大学,生命科学学院,博士,导师: 周丛照/陈宇星
2003/09–2006/07,浙江大学,生命科学学院,硕士,导师: 吴平
1999/09–2003/06,中国科技大学,学士
科研与学术工作经历:
1.2019/12 - 2021/03,Harvard University Division of Medical Sciences,
Dana-Farber Cancer Institute, 访问学者,导师: 刘晓乐 Xiaole Shirley Liu
2.2024/12 - 至今, 安徽中医药大学, 教授
3.2016/11 - 2024/11,安徽中医药大学, 副教授
4.2014/07 - 2016/10,安徽中医药大学,讲师
主持或参加科研项目(课题)情况(只列5项):
1. 安徽省高等学校科学研究项目(自然科学类),2023AH050835,葛根芩连汤通过Nrf2抑制铁死亡改善2型糖尿病肝损伤的分子机制研究,在研,主持
2. 棉花生物育种与综合利用全国重点实验室开放课题,CB2023A25,基于UPLC-QTOF-MS研究棉花花瓣总黄酮干预阿尔兹海默症的活性成分,在研,主持
3. 茶树生物学与资源利用国家重点实验室开放课题重点项目,SKLTOF20210101,黄大茶介导TGF-β/Smad3信号通路缓解糖尿病大鼠肾脏纤维化的分子机制,在研,主持
4. 安徽省教育厅2020年高校自然科学重点项目,KJ2020A0383,基于“肠-菌”互作研究SIRT1通路在葛根芩连汤防治糖尿病肾病的分子机制,结题,主持
5. 安徽省高校优秀拔尖人才培育国外访学项目, gxgwfx2019027,结题,主持
代表性研究成果(近4年):
(1) Zhang X, Ji Z, He Q, Yang D, Wang X, Liu C, Zhang C, Yuan J*, Xu N*, Chu J*. Gegen Qinlian Decoction inhibits liver ferroptosis in type 2 diabetes mellitus models by targeting Nrf2. J Ethnopharmacol. 2024 Dec 26;340:119290. doi: 10.1016/j.jep.2024.119290. (IF: 4.8 Q1 药学1区TOP)
(2) Zhangxin Jia,c1, Chenxu Zhanga,c1, Jingjing Yuana,d, Qing Hea,c, Xinyu Zhanga,c, Dongmei Yanga,c, Na Xub* and Jun Chua,d,e*. Is there a causal association between gestational diabetes mellitus and immune mediators? A bidirectional mendelian randomization analysis. Frontiers in Endocrinology. vol. 15 1358144. 19 Apr. 2024, doi:10.3389/fendo.2024.1358144. (IF:3.9 Q2 医学2区)
(3) Zhangxin Jia,c1, Chenxu Zhanga,c1, Jingjing Yuana,d, Qing Hea,c, Xinyu Zhanga,c, Dongmei Yanga,c, Na Xub* and Jun Chua,d,e*. Predicting the immunity landscape and prognosis with an NCLs signature in liver hepatocellular carcinoma. PLOS ONE. vol. 19,4 e0298775. 25 Apr. 2024, doi:10.1371/journal.pone.0298775. (IF:2.9 Q1 综合期刊3区)
(4) Chenxu Zhang # 1 2, Zhangxin Ji # 1 2, Na Xu 3, Jingjing Yuan 1 4, Wen Zeng 4, Yadong Wang 5, Qing He 1 2, Jiaxing Dong 1 2, Xinyu Zhang 1 2, Dongmei Yang 1 2, Wei Jiang 6, Yibo Yan 7, Wencui Shang 2, Jun Chu 8 9 10, Quangen Chu 11. Integrating network pharmacology and experimental validation to decipher the pharmacological mechanism of DXXK in treating diabetic kidney injury. Scientific reports. 2024 Sep 27;14(1):22319. doi: 10.1038/s41598-024-73642-y.. (IF:3.8 Q1 综合期刊2区)
(5) Yuan, Jingjing, Yueyun Hu, Dongmei Yang, An Zhou, Shengyong Luo, Na Xu, Jiaxing Dong, Qing He, Chenxu Zhang, Xinyu Zhang, Zhangxin Ji, Qinglin Li* and Jun Chu*. 2024.The Effects of Crataegus pinnatifida and Wolfiporia extensa Combination on Diet-Induced Obesity and Gut Microbiota. Foods 13, no. 11: 1633. https://doi.org/10.3390/foods13111633. (IF:4.7 Q1 农林科学2区)
(6) Xiang-Yu Wang, You-Mei Lin, Xiao-Yan Sun, Ya-Qian Wu, Hui Miao, Jun Chu *, Tian-Wen Bai *, Ying-Long Fu *. A lysosomal targeted fluorescent probe based on BODIPY for monitoring NO in living cells and zebrafish imaging [J]. Sensors and Actuators B: Chemical, Volume 383,2023,133592, https://doi.org/10.1016/j.snb.2023.133592.(co-response author) (IF:8.4, Q1 化学1区 Top)
(7) Dong J, Zhou K, Ge X, and Xu, Na and Wang, Xiao and He, Qing and Zhang, Chenxu and Chu Jun * and Li, Qinglin *. Effects of Extraction Technique on the Content and Antioxidant Activity of Flavonoids from Gossypium Hirsutum linn. Flowers[J]. Molecules, 2022, 27(17): 5627. doi: 10.3390/molecules27175627. (IF:4.6, Q2 化学2区 Top)
(8) Yang Y, Huang H, Cui Z, Chu J *, Du G *. UPLC–MS/MS and Network Pharmacology-Based Analysis of Bioactive Anti-Depression Compounds in Betel Nut. Drug Des Devel ther.2021;15:4827-4836. (IF:4.8, (IF:4.8, Q2 医学3区)
(9) Xiaoqing Wang, Collin Tokheim,Shengqing Stan Gu,Binbin Wang,Qin Tang,Yihao Li,Nicole Traugh,Zexian Zeng ,Yi Zhang,Ziyi Li,Boning Zhang, Jingxin Fu,Tengfei Xiao ,Wei Li ,Clifford A Meyer , Jun Chu ,Peng Jiang ,Paloma Cejas ,Klothilda Lim ,Henry Long ,Myles Brown ,X Shirley Liu .In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target. Cell. 2021 Oct 14;184(21):5357-5374.e22. (IF:64.5 Q1 生物学1区 Top)
(10) Collin Tokheim1,2,11, Xiaoqing Wang1,2,3,11, Richard T. Timms4,5,11,†, Boning Zhang1,2,3,Elijah L. Mena4,5, Binbin Wang6,Cynthia Chen7, Jun Ge6, Jun Chu8,Wubing Zhang6, Stephen J. Elledge5,9,*, Myles Brown3,10,*, X. Shirley Liu1 Systematic Characterization of Mutations Altering Protein Degradation in Human Cancers, Molecular Cell, Mol Cell. 2021 Mar 18;81(6):1292-1308.e11. doi: 10.1016/j.molcel.2021.01.020. Epub 2021 Feb 9. PMID: 33567269. (IF:16.0 Q1 生物学1区 Top)
(11) Na Xu#,Jun Chu#,Rongrong Dong, Fengjuan Lu,Xinfeng Zhang, Min Wang, Ying Shen, Zhongwen Xie, Chi-Tang He, CS Yang, Yijun Wang, Xiaochun Wan*Yellow Tea Stimulates Thermogenesis in Mice Through Heterogeneous Browning of Adipose Tissues, Molecular Nutrition and Food Research, 2021 Jan;65(2):e2000864. doi: 10.1002/mnfr.202000864. Epub 2021 Jan 7. PMID: 33258303. (IF:5.2 Q1 农林科学2区)
(12) Xiao Wang, Na Xu, Qinglin Li, Shengqi Chen, Hui Cheng , Mo Yang , Ting Jiang, Jun Chu *, Xiaojing Ma and Dengke Yin,Lactonic Sophorolipids-induced apoptosis in human HepG2 cells through the Caspase-3 pathway, Applied Microbiology and Biotechnology, (2021) 105:2033–2042 (IF:5.0 Q1 工程技术2区 Top)
专利:
1、一种响应面法优化提取棉花鲜花总黄酮的方法(专利号:ZL 2019 1 0235997.1)
四、主要研究方向,研究生带教情况
中药复方干预糖脂代谢性疾病;已毕业研究生4人,在读6人。已经毕业的研究生毕业去向包括各地药企和事业单位,在读期间有多名同学获得研究生特等奖学金等。
本人同时可以招收药学专硕研究生,欢迎邮件咨询。
五、联系方式
邮箱:chuj@ahtcm.edu.cn