
一、个人简介
谭松,男,1989年12月出生,副教授,首都师范大学博士,美国西北大学博士后,安徽中医药大学硕士生导师,安徽中医药大学食品与生物制药系教师。主持国家自然科学基金青年项目、安徽省自然科学基金青年项目、安徽省高等学校自然科学研究项目等国家级、省级项目多项。以第一作者、通讯作者发表SCI论文9篇。
主要研究方向:药效物质基础;疾病及治疗新靶点研究。
二、主持科研项目情况
(1)安徽高校自然科学研究项目优青项目,2024AH030034,基于K63多聚泛素化激活的免疫功能探究金丝桃苷抗前列腺癌机制,2024-09至2027-09,25万,主持;
(2)国家自然科学基金青年项目,82304542,基于脂筏蛋白重排介导的铁死亡途径研究甲基原薯蓣皂苷抑制前列腺癌机制,2024-01至2026-12,30万,主持。
(3)安徽省自然科学基金青年项目,2208085QH278,基于SREBP2调节的脂筏蛋白重排探讨甲基原薯蓣皂苷抑制前列腺癌的机制,2022-01至2023-12,10万,主持。
(4)安徽高校自然科学研究项目重点项目,KJ2021A0540,甲基原薯蓣皂苷通过调节脂筏蛋白重排抑制前列腺癌的机制,2022-01至2023-12,6万,主持。
(5)安徽中医药大学校级人才支持计划,2020rcyb004,基于脂筏模型探究降脂药对前列腺癌的抑制作用,2021-01至2026-01,10万,主持。
三、近年来发表的代表性学术论文
1. Yi Zhao#, Ruonan Wang#, Chaoyu Hu, Yan Wang, Zengrui Li, Dengke Yin*, Song Tan*. Complanatoside A disrupts copper homeostasis and induces cuproptosis via directly targeting ATOX1 in prostate cancer. Toxicology and Applied Pharmacology, 2025, 496, 117257.
2. Jie Chen#, Yi Zhao#, Xiaoli Wang, Long Zang, Dengke Yin*, Song Tan*. Hyperoside inhibits RNF8-mediated nuclear translocation of β-catenin to repress PD-L1 expression and prostate cancer. Anti-Cancer Agents in Medicinal Chemistry, 2024, 24(6), 464-476.
3. Jie Chen#, Puyan Qin#, Zhanxia Tao, Weijian Ding, Yunlong Yao, Weifang Xu, Dengke Yin*, Song Tan*. Anticancer activity of methyl protodioscin against prostate cancer by modulation of cholesterol-associated MAPK signaling pathway via FOXO1 induction. Biological and Pharmaceutical Bulletin, 2023, 46: 574-585.
4. Song Tan, Shuang Li, Xiu-Yue Zhang, Yu-Meng Li, Peng Zhang, Li-Ping Yin*. Monoubiquitinated MxIRT1 acts as an iron receptor to determine MxIRT1 vacuole degradation or plasma membrane recycling via endocytosis. Plant signaling and behavior, 2022, 17: 2095141.
5. Song Tan, Xi Zhang, Qi Zhang, Yu-Meng Li, Peng Zhang and Li-Ping Yin*. HRM and CRAC in MxIRT1 act as iron sensors to determine MxIRT1 vesicle-PM fusion and metal transport. Plant signaling and behavior, 2022, 17: 2005881.
6. Xiao-Li Wang#, Haiyan Gao#, Song Tan#, Chao Xu, Feng-Qing Xu, Tong-Sheng Wang, Ji-Jun Chu, Yan-Quan Han, De-Ling Wu*, Chuan-Shan Jin*. An integrated approach to uncover quality markers of stir-baking Semen Cuscuta with salt solution preventing recurrent spontaneous abortion based on chemical and metabolomic profiling. Journal of Chromatography B, 2021, 1177: 122727.
7. Song Tan#, Peng Zhang#, Wei Xiao, Bing Feng, Lan-You Chen, Shuang Li, Peng Li, Wei-Zhong Zhao, Xiao-Ting Qi*, Li-Ping Yin*. TMD1 domain and CRAC motif determine the association and disassociation of MxIRT1 with detergent-resistant membranes. Traffic, 2018, 19: 122-137.
8. Song Tan#, Fang Liu#, Xiao-Xi Pan, Yue-Peng Zang, Fei Jin, Wei-Xi Zu, Xiao-Ting Qi, Wei Xiao*, Li-Ping Yin*. CSN6, a subunit of the COP9 signalosome, is involved in early response to iron deficiency in Oryza sativa. Scientific Reports, 2016, 6: 25485.
9. Song Tan, Rui Han, Peng Li, Guang Yang, Shuang Li, Peng Zhang, Wei-Bing Wang, Wei-Zhong Zhao, Li-Ping Yin*. Over-expression of the MxIRT1 gene increases iron and zinc content in rice seeds. Transgenic Research, 2015, 24: 109-122.
四、联系方式
邮箱:tansong_1515@ahtcm.edu.cn
地址:合肥市新站区龙子湖路350号安徽中医药大学药学院230室