
一、 个人简历
周婷婷,博士,海军军医大学药学院药物分析学教研室主任、教授、博士生导师;上海市药物(中药)代谢产物研究重点实验室主任;国家青年岐黄学者,上海市卫生健康委优秀学科带头人;校特级优秀教师。长期从事中药药效物质与代谢研究。主持包括国家自然科学基金4项在内的10余项省部级以上科研及人才项目约1200余万元;以第一/通讯作者在Psychiatry Clin Neurosci、Med Res Rev、Phytomedicine、Food Chem、Biomed Pharmacother等国际权威学术刊物上发表SCI论文38篇,其中IF>10分3篇,IF>5分21篇,研究成果获得国际广泛认可,总引用次数超过1800次。单篇最高他引超过1000次,被web of science纳入molecular biology& genetics学术领域最优秀的前1%之列。申请国家发明专利22项,11项获授权。应邀担任Acta Pharm Sin B(IF=14.5)、J Pharm Anal(IF=8.8)杂志青年编委;Front Pharmacol(IF=5.6)、Front Chem(IF=5.5)、Pharmaceuticals(SCI IF=4.6)客座主编;《药物分析杂志》、《沈阳药科大学学报》、《中草药》、《世界科学技术-中医药现代化杂志》等杂志编委。主编、副主编高等教育出版社、人民卫生出版社、中国中医药出版社等国家级规划教材10余部;入选国家“青年岐黄学者”、上海市卫生健康委优秀学科带头人计划、上海市优秀青年教师资助计划、吴孟超式优秀青年计划、“深蓝”人才工程“领航”人才培养计划。同时担任中国药学会药物分析专业委员会副主任委员,世界中医药学会联合会中药系统科学与工程分会常务理事,上海市药学会理事,上海市药学会药物分析专业委员会副主任委员,中国医药生物技术协会药物分析技术分会常务委员,中华中医药学会中药分析专委会委员,中国仪器仪表学会药物质量分析与程控分会理事。
二、 教学科研情况(包括主要在研课题、获奖成果等)
1. 国家青年岐黄学者计划,2023/01-2025/12,主持
2. 上海市卫生健康委学科带头人计划,2023/01-2025/12,主持。
3. 上海市科委“科技创新行动计划”生物医药科技支撑专项,抗抑郁栀子豉汤颗粒临床前研究,2021/8-2024/7,主持。
4. 上海市药学科技奖二等奖,第一完成人。
5. 上海市优秀教学成果一等奖,第一完成人。
6. 上海市一流本科课程《药物分析》,课程负责人。
7. 海军优秀课程《药物分析》,课程负责人。
8. 全国高等学校药学类专业青年教师教学能力大赛一等奖,第一完成人。
9. 全国高等学校药学类专业青年教师微课教学大赛一等奖,第一完成人。
三、 论著情况(包括代表性论文、专著、教材)
代表性论文
(1) Yuye Gao, Tingting Zhou*(通讯作者). Acupuncture: A beacon of hope for primary insomnia. Sleep Med Rev. 2024, 74:101911. (IF 10.5)
(2) Yusha Luo, Tingting Zhou*(通讯作者). Connecting the dots: targeting the microbiome in drug toxicity. Medicinal Research Reviews. 2022,42:83-111. (IF 13.3)
(3) Ruirui Chang#, Jialin Liu#, Yusha Luo#, Taohong Huang, Qi Li, Jun Wen*, Weidong Chen*, Tingting Zhou*(通讯作者). Isoflavones' effects on pharmacokinetic profiles of main iridoids from Gardeniae Fructus in rats. Journal of Pharmaceutical Analysis. 2020, 10:571-580. (IF 8.8)
(4) Xiqing Bian#, Na Zhou#, Yiran Zhao#, Yichao Fang, Na Li, Xin Zhang, Xuan Wang, Yunxia Li, Jian-Lin Wu*, Tingting Zhou*(通讯作者). Identification of Proline, 1-pyrroline-5-carboxylate, and glutamic acid as biomarkers of depression reflecting brain metabolism using carboxylomics, a new metabolomics method. Psychiatry and Clinical Neurosciences, 2023, 77: 196-204. (IF 11.9)
(5) Wen Miao#, Xiaojing Liu#, Na Li, Xiqing Bian, Yiran Zhao, Jing He, Tingting Zhou*(共同通讯作者), Jian-Lin Wu*. Polarity-extended composition profiling via LC-MS-based metabolomics approaches: A key to functional investigation of Citrus aurantium L. Food Chemistry, 2023, 405: 134988. (IF 8.8)
(6) Yuye Gao, Yu Fu, Na Li, Yuetong Jiang, Xiaojing Liu, Congcong Gao, Lishuang Wang, Jian-Lin Wu*, Tingting Zhou*(通讯作者). Carboxyl-containing Components Delineation via Feature-based Molecular Networking: A Key to Processing Conditions of Fermented Soybean. Food Chemistry, 2023, 423: 136321. (IF 8.8)
(7) Jialin Liu#, Yichao Fang#, Lixun Cui#, Zhongzhao Wang, Yusha Luo, Congcong Gao, Wen Ge, Taohong Huang, Jun Wen, Tingting Zhou*(通讯作者). Butyrate emerges as a crucial effector of Zhi-Zi-Chi decoctions to ameliorate depression via multiple pathways of brain-gut axis. Biomed Pharmacother. 2022, 149:112861. (IF 7.5)
(8) Yusha Luo#, Xingjie Zhang#, Wen Zhang#, Qiliang Yang, Wei You, Jun Wen*, Tingting Zhou*(通讯作者).Compatibility with Semen Sojae Praeparatum attenuates hepatotoxicity of Gardeniae Fructus by regulating the microbiota, promoting butyrate production and activating antioxidant response. Phytomedicine. 2021, 90: 153656. (IF 7.8)
(9) Fang-Yuan Gao#, Hai-Yan Chen#, Yu-Sha Luo#, Ji-Kuai Chen, Lang Yan, Jiang-Bo Zhu*, Guo-Rong Fan*, Ting-Ting Zhou*(通讯作者).”Q-markers targeted screening” strategy for comprehensive qualitative and quantitative analysis in fingerprints of Angelica dahurica with chemometric methods. Food Chemistry: X. 12 (2021) 100162. (IF 6.1)
(10) Yin Zhang#, Yichao Fang#, Lixun Cui#, Yuetong Jiang, Yusha Luo, Wen Zhang, Dexun Yu, Jun Wen*, Tingting Zhou*(通讯作者). Zhi-zi-chi decoction reverses depressive behaviors in CUMS rats by reducing oxidative stress injury via regulating GSH/GSSG pathway. Frontiers in Pharmacology. 2022,13: 887890. (IF 5.6)
(11) Yin Zhang# , Yusha Luo#, Dongqi Zhang, Bo Pang, Jun Wen*, Tingting Zhou*(通讯作者). Predicting a Potential Link to Antidepressant Effect: Neuroprotection of Zhi-zi-chi Decoction on Glutamate-induced Cytotoxicity in PC12 Cells. Frontiers in Pharmacology. 2021, 11:625108. (IF 5.6)
(12) Yusha Luo#, Fangyuan Gao#, Ruirui Chang#, Xingjie Zhang, Jie Zhong, Jun Wen*, Jianlin Wu*, Tingting Zhou*(通讯作者). Metabolomics Based Comprehensive Investigation of Gardeniae Fructus Induced Hepatotoxicity. Food and Chemical Toxicology. 2021, 153:112250. (IF 4.3)
(13) Fang-Yuan Gao#, Xue-Feng Chen#, Li-Xun Cui#, Yu-Jia Zhai, Jia-Lin Liu, Cong-Cong Gao, Yi-Chao Fang, Tao-Hong Huang, Jun Wen*, Ting-Ting Zhou*(通讯作者). Gut microbiota mediates the pharmacokinetics of Zhi-zi-chi decoction for the personalized treatment of depression, Journal of Ethnopharmacology, 2023, 302: 115934. (IF 5.4)
(14) Yichao Fang, Tingting Zhou*(通讯作者). Editorial: Antidepressant mechanisms of natural products based on multi-omics technologies. Frontiers in Pharmacology, 2023, 14: 1135791. (IF 5.6)
(15) Hui Guo#, Xiaojing Liu#, Yuetong Jiang#, Jing He, Hongyuan Hao, Taohong Huang, Jian-Lin Wu, Jun Wen*, Tingting Zhou*(通讯作者). Characterization and quantification of the Chinese medical formula Zhi-Zi-Chi decoction, a systematic strategy for the attenuation and synergy of compatibility mechanism. Journal of Pharmaceutical and Biomedical Analysis, 2023, 223: 115130. (IF 3.4)
(16) Yin Zhang#, Yuan Yao#, Xiaolei Shi, Jun Fan, Taohong Huang, Jun Wen, Tingting Zhou*(通讯作者). Combination of cell metabolomics and pharmacology: A novel strategy to investigate the neuroprotective effect of Zhi-zi-chi decoction, Journal of Ethnopharmacology, 2019, 236:302-315. (IF 5.4)
(17) Hui Guo#, Zhen Zhang#, Yuan Yao, Jialin Liu, Ruirui Chang, Zhao Liu, Hongyuan Hao, Taohong Huang, Jun Wen, Tingting Zhou*(通讯作者). A new strategy for statistical analysis-based fingerprint establishment: Application to quality assessment of Semen sojae praeparatum. Food Chemistry, 2018, 258: 189-198. (IF 8.8)
(18) Jialin Liu#, Ruirui Chang#, Xiaobei Zhang, Zhongzhao Wang, Jun Wen, Tingting Zhou*(通讯作者). Non-isoflavones Diet Incurred Metabolic Modifications Induced by Constipation in Rats via Targeting Gut Microbiota. Frontiers in Microbiology, 2018, 9: 3002. (IF 5.2)
(19) Yuan Yao#, Xin Ma#, Teng Li#, Hui Guo, Ruirui Chang, Jialin Liu, Qiaoxia Liu, Hongyuan, Hao, Taohong Huang, Weidong Chen*, Jun Wen*, Tingting Zhou*(通讯作者). Quantification of isoflavone glycosides and aglycones in rat plasma by LC-MS/MS: Troubleshooting of interference from food and its application to pharmacokinetic study of Semen Sojae Praeparatum extract. Journal of Pharmaceutical and Biomedical Analysis, 2018, 161:444-454. (IF 3.4)
参编教材
(1)高等教育出版社《分析化学》,2024,主编
(2)人民卫生出版社《中国医学教育题库(药学专业题库)》,2019,副主编
(3)人民卫生电子音像出版社《药物分析实验操作规范与安全技能教程》,2023,副主编
(4)中国医药科技出版社《中药质量分析与评价》,2024,编委
(5)中国医药科技出版社《中药分析学(第3版)》2023,编委
(6)科学出版社《基础药物分析》,2023,编委
(7)科学出版社《中药分析学》,2022,编委
(8)中国中医药出版社《中药分析学》,2021,编委
(9)中国医药科技出版社《药物分析(第4版)》2019,编委
(10)清华大学出版社《药物分析学(第2版)》2018,编委
(11)中国医药科技出版社《药物分析(第3版)》2017,编委
(12)北京科学技术出版社《中药药物代谢动力学》2017,编委
四、 主要研究方向,研究生带教情况
主要研究方向:药物质量控制、体内代谢及中药药效物质研究;肠道菌群介导的药物(天然产物)药效作用机制研究
研究生带教情况:指导多名硕士研究生获岛津杯全国药物分析优秀论文评选交流会优秀论文二等奖2项,第二届药学研究生学术研讨会三等奖1项,上海市药学会青年论文报告会特等奖、一等奖、二等奖30余项;指导研究生发表SCI研究论文30余篇和中文核心期刊论10余篇;指导2020级硕士研究生高葱葱获安徽中医药大学优秀硕士学位论文。
五、 联系方式:办公电话(系统安全问题,不要留手机号)、邮箱
办公电话:021-81871262
邮箱:tingting_zoo@163.com