
一、个人简历
张发雷,男,1994年10月生,中共党员,校聘研究员,中药学专业硕士研究生导师,中国海洋大学博士。主持安徽中医药大学人才引进项目1项。以第一作者(含共同第一作者)在Journal of the American Chemical Society、Organic Letters、Phytochemistry、Marine Drugs、RSC Advances等国际学术期刊发表SCI论文10篇。主要研究方向为中药内生真菌天然产物的生物合成与合成生物学研究。
二、主持科研项目
(1)安徽中医药大学人才引进项目,2025–2030,50万元,在研,主持。
三、代表性学术论文
(1)Falei Zhang#, Chuanteng Ma#, Meilin Zhu#, Yinghan Chen, Wenxue Wang, Guojian Zhang, Tianjiao Zhu, Qian Che, and Dehai Li*. Biosynthesis of dothideomins reveals a fungal P450 that constructs the tricyclo[5.2.2.0.4,8]undecane-imbedded core skeleton. J. Am. Chem. Soc., 2025, 147, 7094-7102.(自然指数期刊,中科院一区TOP)
(2)Falei Zhang, Chuanteng Ma, Wenxue Wang, Meilin Zhu, Guojian Zhang, Tianjiao Zhu, Qian Che, and Dehai Li*. Insights into the natural occurrence of monomeric and dimeric chromanone lactones. Org. Lett., 2025, 27, 7482-7487.(自然指数期刊,中科院一区TOP)
(3)Falei Zhang#, Chuanteng Ma#, Qian Che, Tianjiao Zhu, Guojian Zhang, and Dehai Li*. Extending the structural diversity of labdane diterpenoids from marine-derived fungus Talaromyces sp. HDN151403 using heterologous expression. Mar. Drugs, 2023, 21, 628.(中科院二区)
(4)Fa-Lei Zhang, Hui-Xiang Yang, Xing Wu, Jia-Yi Li, Shi-Qin Wang, Juan He, Zheng-Hui Li, Tao Feng*, and Ji-Kai Liu*. Chemical constituents and their cytotoxicities from mushroom Tricholoma imbricatum. Phytochemistry, 2020, 177, 112431.(中科院二区)
(5)Fa-Lei Zhang#, Chen Shi#, Li-Tang Sun, Hui-Xiang Yang, Juan He, Zheng-Hui Li, Tao Feng*, and Ji-Kai Liu*. Chemical constituents and their biological activities from the mushroom Pyropolyporus fomentarius. Phytochemistry, 2021, 183, 112625.(中科院二区)
(6)Fa-Lei Zhang and Tao Feng*. Diterpenes specially produced by fungi: Structures, biological activities, and biosynthesis (2010–2020). J. Fungi, 2022, 8, 244. (中科院二区)
(7)Fa-Lei Zhang, Juan He, Tao Feng*, and Ji-Kai Liu*. Melodinines Y1–Y4, four monoterpene indole alkaloids from Melodinus henryi. RSC Advances, 2021, 11, 23-29.(中科院三区)
(8)Xiao Xu#, Falei Zhang#, Luning Zhou, Yimin Chang, Qian Che, Tianjiao Zhu, Dehai Li, and Guojian Zhang*. Overexpression of global regulator SCrp leads to the discovery of new angucyclines in Streptomyces sp. XS-16. Mar. Drugs, 2023, 21, 240.(中科院二区)
(9)Quan Dai#, Fa-Lei Zhang#, and Tao Feng*. Sesquiterpenoids specially produced by fungi: Structures, biological activities, chemical and biosynthesis (2015–2020). J. Fungi, 2021, 7, 1026.(中科院二区)
(10)Juan He#, Fa-Lei Zhang#, Zheng-Hui Li, Hui-Xiang Yang, Qian Shao, Tao Feng*, and Ji-Kai Liu*. Monoterpenoid indole alkaloids from the bark of Melodinus henryi. Fitoterapia, 2019, 138, 104354.(中科院三区)
四、主要研究方向,研究生带教情况
中药内生真菌天然产物的生物合成与合成生物学研究。
可招收中药学学硕、中药学专硕。
五、联系方式
邮箱:faleizhang@outlook.com;flzhang@ahtcm.edu.cn。