夏 泉,男,1969.3,安徽医科大学第一附属医院,博士,主任药师,副教授,药剂科主任。
一、教学科研情况
(1)主持2021年国家自然基金面上项目“基于AMPK-Src/Tensin-整合素αⅡbβ3双向信号通路探讨莪术二酮调控血小板活化作用机制”(82174011),2022.1-2025.12。
(2)主持2022年安徽省教学研究重点项目“研究型教学模式在临床药学实习中的探索”(2022jyxm767),2023.1-2024.12。
二、论著情况
(1)韩功伟, 张腾, 赵营莉, 刘沁华, 夏泉. 伊布替尼血药浓度检测方法的建立及临床应用. 中国药房,2023,34(22):2756-2759.
(2)檀廷飞,程紫薇,韩功伟,夏梓橦,宋帅,夏泉. 血小板胞内摄取莪术二酮的实验研究. 药物分析杂志,2023,43(2):253-261.
(3)张莉,江洁美,檀廷飞,尚茂林,王小华,夏泉. 肺癌患者血浆中安罗替尼浓度与不良反应的相关性研究. 中国医院药学杂志,2022,42(18): 1876-1881
(4)Tingfei Tan, Gongwei Han, Ziwei Cheng, Jiemei Jiang, Li Zhang, Zitong Xia, Xinmeng Wang, Xia Q. Genetic Polymorphisms in CYP2C19 Cause Changes in Plasma Levels and Adverse Reactions to Anlotinib in Chinese Patients With Lung Cancer. Front Pharmacol. 2022, 13:918219.(通讯作者)
(5)Tingfei Tan, Qi Huang, Weiwei Chu, Bo Li, Jingjing Wu, Quan Xia*, and Xi Cao*. Delivery of germacrone (GER) using macrophages-targeted polymeric nanoparticles and its application in rheumatoid arthritis. Drug Delivery. 2022, 29(1):692–701(共同通讯作者)
(6)Beibei Gao, Tingfei Tan, Xi Cao, Menglu Pan, Chunlan Yang, Jianxiong Wang, Zongwen Shuai and Quan Xia. Relationship of cytochrome P450 gene polymorphisms with blood concentrations of hydroxychloroquine and its metabolites and adverse drug reactions. BMC Medical Genomics. 2022, 15: 23(通讯作者)
(7)Li Yao#, Liuli Ren#, Qi Chen#, Yuhan Wu, Jianguo Xu, Quan Xia*, Chao Zhang, Wei Chen*. Rapid and direct concentration range judgment of lamotrigine in plasma by the multi test lines with different detection limits on the same lateral flow strip. Analytica Chimica Acta. 2022, 1192: 339347.(共同通讯作者)
(8)Xing Fang, TingFei Tan, BeiBei Gao, YingLi Zhao, TingTing Liu* and Quan Xia*. Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells. Front. Oncol. 2020, 10: 537322.(通讯作者)
(9)赵营莉,李娟,方兴,高贝贝,檀庭飞,宫鹏,夏泉. 蒙古黄芪和膜荚黄芪水溶性蛋白表达. 中国实验方剂学杂志,2020, 26(5):137-144 (通讯作者)
(10)高贝贝,潘梦璐,杨春兰,宋帅,帅宗文,夏泉. 自身免疫性疾病患者CYP450基因多态性与羟氯喹不良反应及血药浓度的相关性研究. 中国药房,2019,30(9):1251-1255(通讯作者)
(11)任刘丽,赵营莉,高贝贝,宋帅,代贝贝,夏泉. 半定量快速检测拉莫三嗪血药浓度胶体金试纸条的研制及应用. 中国临床药学杂志,2019, 28(4):269-273 (通讯作者)
(12)Hui Fang, Beibei Gao, Yingli Zhao, Xing Fang, Maohong Bian, and Quan Xia. Curdione inhibits thrombin-induced platelet aggregation via regulating the AMP-activated protein kinase-vinculin/talin-integrin αIIbβ3 signaling pathway. Phytomedicine. 2019, 61:152859(通讯作者)
三、主要研究方向和研究生带教情况
主要研究方向:(1)中药心脑血管药理;(2)抗肿瘤药物的治疗药物监测。
研究生带教情况:安徽医科大学药学院硕士生导师,每年带教研究生1名。
四、联系方式
安徽省合肥市绩溪路218号 安徽医科大学第一附属医院药剂科
电话:0551-62922154
邮箱:xiaquan2010@163.com