导师简介-陈茂文

发布者:研究生院 发布时间:2024-03-28 浏览次数:


一、个人简历

陈茂文,男,中共党员,校聘教授,硕士生导师,毕业于重庆大学,获生物医学工程学博士学位。

先后主持包括国家自然科学基金青年基金、安徽省自然科学基金青年基金、安徽省教育厅重点项目等国家级和省部级项目多项。已发表SCI科研论文20余篇,其中,以第一作者的身份在ACS Nano和Chem.Eng.J.等TOP期刊发表SCI论文8篇,影响因子IF>10的4篇,单篇最高影响因子18.027。

二、代表性学术论著:

1.MW Chen, D Wang, MH Li, Y He, TT He, MH Chen, Y Hu* Z Luo* and KY Cai* Nanocatalytic Biofunctional MOF Coating on Titanium Implants Promotes Osteoporotic Bone Regeneration through Cooperative Pro-osteoblastogenesis MSC Reprogramming. ACS Nano 2022,16,9:15397-15412. (IF= 18.027, SCI一区)

2.MW Chen, Y Hu*, YH Hou, MH Li, L Tan, MH Chen, WB Geng, BL Tao, Z Luo*, KY Cai*. Magnesium/gallium-layered nanosheets on titanium implants mediate osteogenic differentiation of MSCs and osseointegration under osteoporotic condition. Chemical Engineering Journal, 2022,427: 130982. (IF:16.744, SCI一区)

3.D Wang, MW Chen, YJ Wei, WB Geng, Y Hu, Z Luo, KY Cai. Construction of Wogonin Nanoparticle-Containing Strontium-Doped Nanoporous Structure on Titanium Surface to Promote Osteoporosis Fracture Repair. Advanced Healthcare Materials. 2022,2201405. (IF:11.092, SCI二区, 共同一作)

4.WB Geng, MW Chen, BL Tao, R Wang, D Wang, K Li, CC Lin, XZ Liu, PF Gao, Z Luo*, KY Cai*. Cell-free DNA depletion via cell-penetrating poly(disulfide)s for rheumatoid arthritis therapy. Applied Materials Today, 2022, 26:101351. (IF:8.663, SCI二区, 共同一作)

5.MW Chen, Yan Hu*, Yanhua Hou, Menghuan Li, Maohua Chen, Caiyun Mu, Bailong Tao, Wei Zhu, Zhong Luo* and Kaiyong Cai*. Differentiation regulation of mesenchymal stem cells via autophagy induced by structurally different silica based nanobiomaterials. J. Mater. Chem. B, 2019,7: 2657-2666. (IF:7.571, SCI二区)

6.MW Chen, Yan Hu*, Yanhu Hou, Menghua Li, Maohua Chen, Lu Tan, Caiyun Mu, Bailong Tao, Zhong Luo*, Kaiyong Cai*. Osteogenesis regulation of mesenchymal stem cells via autophagy induced by Silica-Titanium composite surfaces with different mechanical modulus. J. Mater. Chem. B, 2020, 8: 9314-9324. (IF:7.571, SCI二区)

7.MW Chen, Bailong Tao, Lu Tan, Yan Hu*, Menghuan Li, Maohua Chen, Caiyun Mu, Zhong Luo*, Kaiyong Cai*. Enhanced Biocompatibility and Osteogenic Differentiation of Mesenchymal Stem Cells of Titanium by Sr-Ga Clavate Double Hydroxides. J. Mater. Chem. B, 2021, 9: 6029-6036. (IF:7.571, SCI二区)

三、主持或参与科研项目情况

1.国家自然科学基金项目,青年项目,82302670,2024/01-2026/12,30万,在研,主持

2.安徽省自然科学基金项目,青年项目,2308085QH256,2023/09-2025/8,8万,在研,主持;

3.安徽省教育厅,重点项目,2022AH050441,2023-01-01至2025-01-01,10 万元,在研,主持

4.安徽中医药大学高层次人才支持计划,2023rcZD004,2022-09-15至2028-09-15,35万元,在研,主持

5. 国家自然科学基金委员会,面上项目,51773023,2018-01-01至2021-12-31,61 万元,结题,参与

四、主要研究方向

1.植物药物提取、纳米颗粒材料和水凝胶材料的设计与合成:用于探究对骨相关细胞的影响分子机制及体内外生物学评价;

2.骨科植入材料开发:基于骨代谢与骨质疏松等病理微环境机制的探究,研发具有局部抗骨质疏松性能的骨科植入材料,提高骨质疏松性骨折的内固定成功率。

五、联系方式

邮箱:maowen_chen@ahtcm.edu.cn

QQ:458543044