
一、个人简历
邢世海,男,博士、博士后,安徽庐江人,安徽中医药大学教授(其中2017-2021为校特聘教授,2021-至今教授),硕士/博士研究生导师、博士后合作导师。主要研究方向:中药生物技术、分子生药学。主持国家自然科学基金面上项目、中国博士后基金、上海市科技委员会项目、安徽省科技厅自然科学基金面上项目等国家、省部级项目9项,已结题7项,在研国家、省部级项目2项;参与国家863、973项目,科技部专项及国家自然科学基金区域联合基金项目等。发表文章50余篇,其中SCI论文40余篇,获授权专利3件,担任10余本植物学相关SCI期刊审稿专家,参与编写教材2部,参与制定团体标准1项,获批中药植物新品种2件。
学习与工作经历:
1996-2003 西北农林科技大学 学士(林学)
2000-2003 西北农林科技大学 硕士(森林培育学)
2007-2011 上海交通大学博士(植物学)
2012-2014 中科院上海生命科学研究院博士后(生物学)
2014-2017 美国密西西比州立大学博士后(生化与分子生物学)
2017-2021 安徽中医药大学 校特聘教授、硕士生导师
2021-至今 安徽中医药大学 教授、硕士/博生生导师,博士后合作导师
主要兼职:
任国家自然科学基金评审专家、国际学术期刊Chemosphere(2017年2月-至今)、Industrial Crops and Products(2022年5月-)、Journal of Ethnopharmacology(2022年7月-)、Frontiers in nutrition(2022年7月-)、Plant Cell Reports(2024年7月-)、Frontiers in Plant Science(2021年5月-)、Scientia Horticulturae(2022年5月-)等期刊审稿专家、《Chinese Herbal Medicines》杂志第一届青年编辑委员会委员(2019.10-2021.10)、中国遗传学会终身高级会员(S261211253S)等。
主持主要项目:
主持国家自然科学基金面上项目(82474037)、中国博士后基金项目(2013M541556)、安徽省科技厅自然科学基金面上项目(1908085MH268)、安徽省教育厅自然科学重点项目(KJ2019A0453、2022AH050461)、上海市科技委员会项目(G142425、F132425)、安徽省人社厅归国人员项目等近20项。在研国家、省部级项目2项。
二、教学科研情况
教学情况:
开设过本科课程包括:《生物技术制药概论》、《药用植物组织培养》、《药学英语》、《中药生物技术》、《生物统计与实验设计》和《植物生物技术》等。
现承担中药学本科专业《药用植物组织培养》和生物制药本科专业《生物技术制药概论》课程。
在研主要项目:
[1] 合肥综合性国家科学研究中心大健康研究院安徽中药材种植联合研究中心, 重点项目, yjzx2023001, 亳菊花形转录调控机理及分子育种技术研究, 2023-09 至 2025-08, 100万元, 在研, 主持 (横向课题)
[2] 国家自然科学基金委,国家自然科学基金面上项目, 82473805, DhDof5转录因子响应低温低湿调控霍山石斛甘露糖生物合成分子机理的研究, 2025-01至2028-12, 48万元, 在研, 主持 (国家课题)
作为研究生导师指导研究生发表的主要论文:
[1] Cao MY, Liu YY, Jiang WM, Meng XX, Zhang W, Chen WD, Peng DY, Xing SH*. UPLC/MS-based untargeted metabolomics reveals the changes of metabolites profile of Salvia miltiorrhiza bunge during Sweating processing [J]. Scientific Reports, 2020, 10: 19524. (通讯作者)
[2] Su XL, Liu YY, Han L, Wang ZJ, Cao MY, Wu LP, Jiang WM, Meng F, Guo XH, Yu NJ, Gui SY, Xing SH*, Peng DY*. Candidate gene identified in converting platycoside E to platycodin D from Platycodon grandiflorus by transcriptome and main metabolites analysis [J]. Scientific Reports, 2021, 11: 9810. (通讯作者)
[3] Wang ZJ#, Jiang WM#, Liu YY, Su XL, Cao MY, Wu LP, Yu NJ, Xing SH*, Peng DY*. Putative genes in alkaloid biosynthesis identified in Dendrobium officinale by correlating the contents of major bioactive metabolites with genes expression between Protocorm-like bodies and leaves [J]. BMC Genomics, 2021, 22: 579. (通讯作者)
[4] Zhang J, Huang HZ, Qu CQ, Meng XX, Meng F, Yao XY, Wu J, Guo XH, Han BX, Xing SH*. Comprehensive analysis of chloroplast genome of Albizia julibrissin Durazz. (Leguminosae sp.) [J]. Planta, 2021, 10.1007/s00425-021-03812- z. (通讯作者)
[5] Wu J, Meng XX, Jiang WM, Wang ZJ, Zhang J, Meng F, Yao XY, Ye MJ, Yao L, Wang LH, Yu NJ, Peng DY*, Xing SH*. Qualitative proteome-wide analysis reveals the diverse functions of lysine crotonylation in Dendrobium huoshanese [J]. Frontiers in Plant Science, 2022, 10.3389/fpls.2022.822374. (通讯作者)
[6] Guo XH, Meng XX, Li Y, Qu CQ, Liu YY, Cao MY, Yao XY, Meng F, Wu J, Peng HS, Peng DY, Xing SH*, Jiang WM*. Comparative proteomics reveals biochemical changes in Salvia miltiorrhiza Bunge during sweating processing [J]. Journal of Ethnopharmacology, 2022, 293: 115329. (通讯作者)
[7] Su XL, Meng F, Liu YY, Jiang WM, Wang ZJ, Wu LP, Guo XH, Yao XY, Wu J, Sun ZP, Zha LP, Gui SY, Peng DY, Xing SH*. Molecular Cloning and Functional Characterization of A β-Glucosidase Gene to Produce Platycodin D in Platycodon grandiflorus [J]. Frontiers in Plant Science, 2022, DOI: 10.3389/fpls.2022.955628. (通讯作者)
[8] Wu LP, Meng XX, Huang HZ, Liu YY, Jiang WM, Su XL, Wang ZJ, Meng F, Wang LH, Peng DY*, Xing SH*. Comparative Proteome and Phosphoproteome Analyses Reveal Different Molecular Mechanism between Stone Planting Under the Forest and Greenhouse Planting of Dendrobium huoshanense [J]. Frontiers in Plant Science, 2022, DOI: 10.3389/fpls.2022.937392. (通讯作者)
[9] Yao XY, Meng F, Wu LP, Guo XH, Sun ZP, Jiang WM, Zhang J, Wu J, Wang ST, Wang ZJ, Su XL, Dai XR, Qu CQ, Xing SH*. Genome-wide identification of R2R3-MYB family genes and gene response to stress in Zingiber officinale Roscoe [J]. The Plant Genome, 2022, DOI:10.1002/tpg2.20258. (通讯作者)
[10] Wang ZJ, Wu J, Sun ZP, Jiang WM, Liu YY, Tang J, Meng XX, Su XL, Wu LP, Wang LH, Guo XH, Peng DY, Xing SH*. ICP-MS based metallomics and GC-MS based metabolomics reveals the physiological and metabolic responses of Dendrobium huoshanense plants exposed to Fe3O4 nanoparticles [J], Frontiers in nutrition, 2022, DOI: 10.3389/fnut.2022.1013756. (通讯作者)
[11] Wu J, Zhang J, Guo XH, Yu NJ, Peng DY*, XING SH*. Comprehensive analysis of complete chloroplast genome sequence of Plantago asiatica L. (Plantaginaceae) [J]. Plant Signaling & Behavior, 2023, https: //doi.org/10.1080/1559232. (通讯作者)
[12] Yu-ting Wang, Xue-qing Fu, Li-hui Xie, Wei Qin, Ling Li, Xiao-fen Sun, Shi-hai Xing*, Ke-xuan Tang*. Stress Associated Protein 1 regulates the development of glandular trichomes in Artemisia annua [J]. Plant Cell, Tissue and Organ Culture, 2019, https://doi.org/10.1007/s11240-019-01677-5. (通讯作者)
[13] Wu J, Yu NJ, Peng DY, et al. The Partial Chloroplast Genome of Hypericum monogynum L. (Guttiferae) [J]. AJPS, 2021,12:707-710. (通讯作者)
[14] Wu LP, Fan JZ, Su XL, Peng DY, Xing Shihai*. Genome-wide Identification of R2R3-MYB Family Genes and their Response to Stress in Dendrobium nobile[J]. Frontiers in Bioscience, 2024,29(1): 1. (通讯作者)
[15] Wu LP, Meng F, Su XL, Chen N, Peng DY, Xing SH*. Transcriptomic responses to cold stress in Dendrobium huoshanese C. Z. Tang et S.J.Cheng [J]. Physiology and Molecular Biology of Plants, 2023, https://doi.org/10.1007/s12298-023-01385-7. (通讯作者)
[16] Fan JZ, Chen N, Rao WY, Ding WY, Wang YQ, Duan YY, Wu J, Xing SH*. Genome-wide analysis of bZIP transcription factors and their expression patterns in response to methyl jasmonate and low-temperature stresses in Platycodon grandifloras [J]. Peer J, 2024, 12: e17371. (通讯作者)
[17] Chen N, Fan JZ, Li G, Guo XX, Meng X, Wang YQ, Duan YY, Ding WY, Liu K, Liu YW*, Xing SH*. Comparative Analysis of the Chemical Constituents of Chrysanthemum morifolium with Different Drying Processes Integrating LC/GC–MS−Based, Non-Targeted Metabolomics[J]. Metabolites, 2024, 14: 481. (通讯作者)
[18] Duan YY, Wang YQ, Ding WY, Wang C, Meng L, Chen N, Liu YW*, Xing SH*. Comparative and Phylogenetic Analysis of the Chloroplast Genomes of Four Commonly used Medicinal Cultivars of Chrysanthemums morifolium [J]. BMC Plant Biology, 2024, Doi: 10.1186/s12870-024-05679-0. (通讯作者)
[19] Yang QS, Xu SW, Jiang WM, Meng F, Wang ST, Sun ZP, Chen N, Peng DY, Liu J*, Xing SH*. Systematic qualitative proteome-wide analysis of lysine malonylation profiling in Platycodon grandiflorus. [J]. Amino Acids, 2025, 57:9. (通讯作者)
[20] Ding WY, Duan YY, Wang YQ, Fan JZ, Rao WY, Xing SH*. Qualitative proteomic analysis of lysine malonylation in response to salicylic acid in the roots of Platycodon grandiflorus [J]. International Journal of Molecular Sciences, 2025, 26: 1392. (通讯作者)
[21] Fan JZ, Rao WY, Peng DY, Wei T*, Xing SH*. Genome-wide identification of UGT gene family and functional analysis of PgUGT29 in Platycodon grandiflorus [J]. International Journal of Molecular Sciences, 2025, 26(10): 4832. (通讯作者)
[22] Wang YQ+, Duan YY+, Chen N, Ding WY, Liu YW*, Xing SH*. Integrated physiological, transcriptomic, and metabolomic analyses of Chrysanthemum ‘Boju’ under excessive indole-3-acetic acid stress. Frontiers in Plant Science, 2025, 1531585.(通讯作者)
[23] Rao WY, Fan JZ, Sun ZP, Wang C, Guan JJ, Duan YY, Yu MY, Peng DY, Xing SH*. The role of lysine dihydroxyisobutyrylation in Dendrobium huoshanese under low-temperature by proteomic analysis [J]. Physiologia Plantarum, 2025, 177: e70343.(通讯作者)
[24] Wu J, Wang ST, Xing SH*, Peng DY*. Construction of yeast one-hybrid library of Dendrobium huoshanense and screening of potential transcription factors regulating DhPMM gene expression [J]. biomolecules, 2025, 15: 1251. (通讯作者)
四、主要研究方向,研究生带教情况
主要研究方向:分子生药学、中药生物技术、生物制药
带教研究生情况:已指导毕业硕士生近15人、访问学者1人;在读硕士研究生11人、在站博士后2人。
获奖情况:指导硕士研究生发表科技论文获省级学会二等奖2篇,三等奖3篇,优秀奖1篇;获安徽中医药大学2024、2025年度优秀研究生指导教师。
五、联系方式:
QQ: 924648139,Email: xshshihai@ahtcm.edu.cn