
一、个人简历
徐愿,安徽宿松县人,医学博士,中日友好医院主任医师,现任中医风湿病科副主任,国家中西医结合医学中心综合办公室副主任,中国科学院计算机网络信息中心博士生行业导师。曾任国家自然科学基金委医学科学部中西医结合学流动编制项目主任(2022.3-2024.2),美国耶鲁大学医学院访问学者(2017.12-2018.12)。获得北京中医药新125工程领衔人才、中华中医药学会中青年创新人才、中日友好医院卓越医师等荣誉称号。
兼任中国民族医药学会风湿病分会副会长,中国中医药信息学会免疫分会常委,中华中医药学会青年委员会委员,中华中医药学会风湿病分会委员,the Innovation, Advanced Chinese Medicine,中国中医基础医学杂志,中国实验方剂学杂志青年编委,临床医学工程编委等职务。
二、教学科研情况(包括主要在研课题、获奖成果等)
获得荣誉:获得省部级科技进步奖4项。
主持课题14项,主持的在研课题如下:
国家自然科学基金面上项目(82474275),治尪汤调控FABP4/OPA1/TRPA1通路恢复神经元线粒体功能稳态缓解RA寒痹证疼痛敏化的机制研究,49万,2025.1-2028.12
北京市自然科学基金(7232319),治尪汤从FLS细胞FAPα介导的炎症/破骨交联改善类风湿关节炎骨破坏的机制研究,20万,2023.1-2025.12
中日友好医院中央高水平医院临床业务费专项(2025-NHLHCRF-JBGS-B-WZ-10),疏肝定痛法治疗纤维肌痛综合征的疗效预测模型构建与疗效评价研究2025.9 -2027.8,100万
北京市朝阳区卫生健康委(2025SLZZ029),纤维肌痛综合征中医人工智能诊疗模型研究2025.7 -2027.6,10万,主持
三、论著情况(包括代表性论文、专著、教材)
Wang Z, Dong Q, Zhang L, Wang X, Jiao Y, Geng Q, Cai W, Zhang Q, Xiao C, Tao Q*, Xu Y*. Fibroblast activation protein-alpha drives rheumatoid arthritis inflammation through the AKT/mTOR signaling pathway and its therapeutic effect by Wangbi granules[J]. Phytomedicine, 2025, 147: 157179. (JCR Q1区, IF 8.3)
Wang J, Zhang X, Mo M, Zhang N, Tao Q*, Xu Y*. Expert consensus on the advantages of traditional Chinese medicine in the treatment of rheumatoid arthritis[J]. Chin Med, 2025, 20(1): 75. (JCR Q1区, IF 5.5)
Wang Z, Lan T, Jiao Y, Wang X, Yu H, Geng Q, Xu J, Xiao C*, Tao Q*, Xu Y*. Early prediction of bone destruction in rheumatoid arthritis through machine learning analysis of plasma metabolites[J]. Arthritis Res Ther, 2025, 27(1): 111. (JCR Q1区, IF 4.4)
Wang Z, Lan T, Zhang Y, Guo Z, Yu H, Sun G, Wang Z, Yan Z, Tao Q*, Xu Y*. Osteoarthritis and Degree of Fatigue are Associated with Pain Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study of 394 Patients[J]. Int J Gen Med, 2025, 18: 497-507. (JCR Q1区, IF 2.8)
Liu L, Wang J, Chen Y, Fang Y, Wang Z, Liu X, Hong L, Tao Q*, Xu Y*. Efficacy and Safety of the Bushen Quhan Zhiwang Decoction to Achieve Clinical Deep Remission in Rheumatoid Arthritis: Protocol for a Double-Blind, Randomized, Placebo-Controlled Trial[J]. J Pain Res, 2025, 18: 4237-4249. (JCR Q2区, IF 2.5)
Zhang L B, Yan Y, Ma R, Li D X, Yin W F, Tao Q W*, Xu Y*. Integrated phytochemistry and network pharmacology analysis to reveal effective substances and mechanisms of Bushen Quhan Zhiwang decoction in the treatment of rheumatoid arthritis[J]. J Ethnopharmacol, 2024: 117897.(JCR Q1区, IF 5.4)
Yan Y, Zhang L B, Ma R, Wang M N, He J, Wang P P, Tao Q W, Xu Y*. Jolkinolide B ameliorates rheumatoid arthritis by regulating the JAK2/STAT3 signaling pathway[J]. Phytomedicine, 2023, 124: 155311. (中科院 Q1区, IF 7.9)
Zhang N, Zhang L B, Wang Z, Lan T Y, Wang J P, Xiao C, Tao Q W*, Xu Y*. Efficacy and safety of the modified Zhiwang decoction combined with methotrexate in early rheumatoid arthritis: study protocol for a randomised controlled trial[J]. BMJ Open, 2024, 14(1): e76571. (JCR Q2区, IF 2.9)
Jiao Y, Wang X, Wang Q, Geng Q, Cao X, Zhang M, Zhao L, Deng T, Xu Y*, Xiao C*: Mechanisms by which kidney-tonifying Chinese herbs inhibit osteoclastogenesis: Emphasis on immune cells. FRONT PHARMACOL 2023, 14:1077796. (JCR Q1区, IF 5.6)
Wang J, Wang Z, Lan T, Zhang L, Li Z, Wang X, Zou Q, Wang Y, Li Y, Luo R, Zhang N, Xu Y*, Li M*, Tao Q*. Wangbi granule as a combination therapy to achieve clinical deep remission in rheumatoid arthritis: protocol for a multicenter, triple-blind, randomised, placebo-controlled trial[J]. Chin Med,2023,18(1):22. (JCR Q1区, IF 4.9)
Wang Z, Wang J, Lan T, Zhang L, Yan Z, Zhang N, Xu Y*, Tao Q*. Role and mechanism of fibroblast-activated protein-alpha expression on the surface of fibroblast-like synoviocytes in rheumatoid arthritis[J]. Front Immunol,2023,14:1135384. (JCR Q1区, IF 7.3)
四、主要研究方向,研究生带教情况
(一)研究方向
风湿疾病中药药理学研究
风湿疾病发病机制与中医临床研究
(二)研究生带教情况
中国科学院计算机网络信息中心博士生行业导师北京中医药大学,内蒙古医科大学、山西中医药大学、云南中医药大学硕士研究生导师,已毕业硕士研究生3名,在读硕士研究生11名。
五、联系方式:
010-84205067
xuyuan2004020@163.com